腹腔镜胆囊切除术中右美托嘧啶对靶控输注丙泊酚复合瑞芬太尼麻醉深度的影响

发布时间：2018-01-07 07:18

本文关键词：腹腔镜胆囊切除术中右美托嘧啶对靶控输注丙泊酚复合瑞芬太尼麻醉深度的影响　出处：《心血管病防治知识(学术版)》2016年05期 　论文类型：期刊论文

【摘要】：目的探讨腹腔镜胆囊切除术中右美托嘧啶对靶控输注丙泊酚复合瑞芬太尼麻醉深度的影响。方法本次研究选取我院实施腹腔镜胆囊切除术患者66例,分为对照组和观察组,每组33例,对照组采用靶控输注丙泊酚复合瑞芬太尼全身麻醉,观察组在上述基础上输注右旋美托咪啶,对比两组对麻醉深度的影响,以及手术时间,术后拔管时间,苏醒时间和清醒时间的影响。结果两组患者在给药前脑电双频指数(bispectral idex,BIS)比较无显著性差异(P0.05);在给药5min后对照组BIS高于观察组,差异具有统计学意义(P0.05);给药15min后,对照组BIS显著高于观察组,差异具有显著性(P0.01)。两组患者手术时间,术后拔管时间,苏醒时间和清醒时间的影响比较无显著性差异(P0.05)。结论腹腔镜胆囊切除术中右美托嘧啶可以降低BIS,增加麻醉深度,但对患者拔管时间,苏醒时间以及清醒时间无明显影响。
[Abstract]:Objective to investigate the effect of infusion of propofol and remifentanil anesthesia depth on the target control of right dexmedetomidine pyrimidine in laparoscopic cholecystectomy. Methods this study selected 66 cases in our hospital in patients undergoing laparoscopic cholecystectomy, were randomly divided into control group and observation group, 33 cases in each group, the control group using target controlled infusion of propofol and remifentanil anesthesia, observation group on the basis of the above infusion of dexmedetomidine, compared two groups of the depth of anesthesia, and the operative time, postoperative extubation time, recovery time and recovery time. The results of two groups of patients before administration of bispectral index (bispectral, idex, BIS) showed no significant difference (P0.05 BIS); the control group was higher than in the observation group after administration of 5min, the difference was statistically significant (P0.05); after administration of 15min, BIS in control group was significantly higher than the observation group, the difference was significant (P0.01). Two groups of patients with operation time, operation After extubation time, there is no significant difference between the effects of recovery time and awake time (P0.05). BIS can reduce the resection of right dexmedetomidine pyrimidine conclusion laparoscopic cholecystectomy, but to increase the depth of anesthesia, extubation time, had no significant effect on the recovery time and awake time.

【作者单位】：贵州医科大学附属医院;
【分类号】：R614
【正文快照】： 右美托嘧啶(Dexmedetomidine,DEX)是近年来新进的一类高选择性且高效的α2肾上腺素受体激动剂,该物质是美托嘧啶的右旋异构体,具有较强的抑制交感神经活性,在抗焦虑、镇痛、催眠等方面具有良好效果[1]。然而,对于腹腔镜胆囊切除术中右美托嘧啶对靶控输注丙泊酚复合瑞芬太尼麻

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