罗哌卡因对腰硬联合麻醉下子宫全切术患者运动神经阻滞的影响
发布时间:2018-01-08 20:01
本文关键词:罗哌卡因对腰硬联合麻醉下子宫全切术患者运动神经阻滞的影响 出处:《检验医学与临床》2016年15期 论文类型:期刊论文
更多相关文章: 罗哌卡因 腰硬联合麻醉 子宫全切术 运动神经阻滞
【摘要】:目的研究罗哌卡因对腰硬联合麻醉下子宫全切术患者运动神经阻滞的影响。方法收集2014年1月至2015年12月内蒙古自治区妇幼保健医院子宫肿瘤患者108例,将患者随机分为罗哌卡因组和左旋布比卡因组。主要观察指标为术中平均动脉压(MAP)、感觉神经阻滞时间、运动神经阻滞时间和Bromege评分。结果与左旋布比卡因组相比,罗哌卡因组患者运动神经阻滞时间显著缩短[(154.83±35.12)min vs.(190.24±33.06)min,P0.001],Bromege评分显著降低[(2.46±1.06)分vs.(2.89±0.79)分,P=0.02]。两组患者术中各个时间点的MAP、感觉神经阻滞时间、恶心、呕吐和头痛等并发症差异无统计学意义(P0.05)。结论与左旋布比卡因相比,罗哌卡因在腰硬联合麻醉下子宫全切术中是安全有效的,显著降低了患者运动神经阻滞时间。
[Abstract]:Objective to study the effect of ropivacaine on motor nerve block in patients undergoing total hysterectomy under combined spinal-epidural anesthesia. Methods from January 2014 to December 2015, uterine neoplasms in Inner Mongolia Autonomous region Maternal and Child Health Hospital were collected. There were 108 cases. Patients were randomly divided into ropivacaine group and levobupivacaine group. Results compared with the levobupivacaine group, the motor nerve block time of ropivacaine group was significantly shorter than that of levobupivacaine group. [154.83 卤35.12min vs.(190.24 卤33.06min P0.001] Bromege score decreased significantly. [The scores of vs.(2.89 卤0.79 and vs.(2.89 were 2.46 卤1.06 and 0.02 respectively. The time of sensory nerve block and nausea were measured at different time points during operation in the two groups. There was no significant difference in complications such as vomiting and headache. Conclusion compared with levobupivacaine, ropivacaine is safe and effective in total hysterectomy under combined spinal-epidural anesthesia. The time of motor nerve block was significantly decreased.
【作者单位】: 内蒙古自治区妇幼保健院;内蒙古医科大学附属医院;
【基金】:内蒙古自治区自然科学基金项目(2013MS1139)
【分类号】:R614
【正文快照】: 目前,腰硬联合麻醉在外科手术中应用越来越广泛[1],其主要原因是腰硬联合麻醉具有起效快、时间可控性强、肌松完全和术后镇痛方便等优点[2-3]。腰硬联合麻醉的常用麻醉药为罗哌卡因和左旋布比卡因。左旋布比卡因是一种长效酰胺类局麻药,主要通过降低神经细胞膜上钠离子的通透,
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