电针对靶控输注丙泊酚镇静深度的影响

发布时间：2018-01-10 03:18

本文关键词：电针对靶控输注丙泊酚镇静深度的影响　出处：《中国中西医结合外科杂志》2016年06期 　论文类型：期刊论文

【摘要】：目的:观察电针辅助靶控输注丙泊酚脑电双频指数(BIS)和听觉诱发电位指数(AAI)的变化,了解电针对靶控输注丙泊酚时镇静深度的影响。方法:择期全麻患者80例,随机分为对照组(A组)和电针辅助组(B组),A组不接受电针刺激,B组于麻醉诱导前20 min接受电针刺激至术毕。两组均以4μg/m L的效应室靶浓度靶控输注(T_CI)丙泊酚行麻醉诱导和麻醉维持,意识消失后,静脉推注1μg/kg的瑞芬太尼,置入喉罩。观察并记录两组T_CI前(T_0)、T_CI开始后5 min(T_1)、10 min(T_2)、15min(T_3)各时间点的MAP、HR、BIS、AAI值以及诱导至意识消失时所需时间和丙泊酚用量。结果:与A组相比,B组各时间点BIS值、AAI值均小于A组(P0.05),其中BIS值A组为(97±4)、(39±12)、(40±10)、(41±9),B组为(78±9)、(27±7)、(27±9)、(28±8),AAI值A组为(97±5)、(16±4)、(17±4)、(16±3),B组为(77±4)、(10±4)、(11±4)、(10±3),两组MAP、HR差异无统计学意义(P0.05)。与T_0比,两组T_1~T_3 BIS值、AAI值以及MAP均明显下降(P0.05),HR无明显变化(P0.05)。意识消失时间A组为(100±14)s,B组为(56±13)s,B组短于A组(P0.05)。丙泊酚诱导用量A组为(155±8)mg,B组为(122±6)mg,B组小于A组(P0.05)。结论:针刺辅助丙泊酚靶控输注时,能增加丙泊酚镇静深度,缩短麻醉诱导时间,减少麻醉诱导剂量。
[Abstract]:Objective: to observe the changes of bispectral index (BIS) and auditory evoked potential index (AAI) of electroacupuncture assisted target controlled infusion of propofol. To investigate the effect of electroacupuncture on sedation depth of target controlled infusion of propofol. Methods: 80 patients with selective general anesthesia were randomly divided into control group (group A) and electroacupuncture supplementary group (group B). Group B received electroacupuncture stimulation 20 min before anesthesia induction until the end of operation. Both groups were anesthetized and maintained with 4 渭 g / mL TCI) propofol. After losing consciousness, 1 渭 g / kg remifentanil was injected intravenously and put into larynx mask. (10 min / T _ 2 / T _ 2 / T _ 3) MAPHR-BIS at each time point. Results: compared with group A, the BIS value of group B was lower than that of group A (P 0.05). The BIS value in group A was 97 卤4, 39 卤12, 40 卤10, 41 卤9, and in group B, it was 78 卤9, 27 卤7, 27 卤9, 28 卤8). The AAI value in group A was 97 卤5, 16 卤4, 17 卤4, 16 卤3, and 10 卤4, 10 卤4, 11 卤4, 10 卤3). There was no significant difference in MAPHR between the two groups (P 0.05). Compared with T _ (0), the value of T1T _ 3 BIS and MAP in the two groups decreased significantly (P _ (0.05)). There was no significant change in HR (P 0.05). The time of consciousness disappearance in group A was 100 卤14s, and that in group B was 56 卤13s. The induced dose of propofol in group A was 155 卤8 mg / g, and that in group B was 122 卤6mg. Conclusion: acupuncture assisted target-controlled infusion of propofol can increase the depth of propofol sedation, shorten the induction time and reduce the dose of anesthesia induction.
【作者单位】：北京市垂杨柳医院微创中心;天津市南开医院麻醉科;
【分类号】：R614
【正文快照】： 随着针刺辅助麻醉(acupuncture-assisted anes-1.2治疗方法未用术前药。常规连接生命体征thesia,AAA)的开展,人们对其作用有了许多新认检测仪(Datax公司,芬兰)监测心电图(ECG)、平均识,相关研究涉及到整个围手术期,包括术前镇静、动脉压(MAP)、心率(HR)及脉搏血氧饱和度(Sp O2

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