不同丙泊酚制剂麻醉对高脂血症患者围术期血脂水平的影响

发布时间：2018-01-12 18:27

  本文关键词：不同丙泊酚制剂麻醉对高脂血症患者围术期血脂水平的影响　出处：《中外医疗》2016年15期 　论文类型：期刊论文

  更多相关文章： 丙泊酚 高脂血症 长链脂肪酸 中长链脂肪酸

【摘要】：目的探讨高血脂患者应用不同丙泊酚制剂手术麻醉对其围手术期血脂水平的影响。方法方便选取2014年1月—2015年12月收治的高脂血症手术患者90例,随机分3组,各30例,A组采用吸入七氟醚维持全麻,B组使用规格为50 m L/500 mg的长链脂肪酸,C组使用规格为20 m L/200mg的中长链脂肪酸,比较各组在围手术期的血脂水平变化。结果各组手术后血脂水平较T0时均有明显变化,B、C两组在T1时LDL值和TC值均有明显下降,C组下降幅度B组;比较差异有统计学意义(P0.05);T2时B、C两组TG水平明显下降;T3时B组HDL值明显上升。结论丙泊酚长链脂肪酸对患者围手术期的血脂水平变化影响较小,为高血脂症患者手术麻醉的更为安全的选择。
[Abstract]:Objective to investigate the effect of anesthesia with different propofol preparations on serum lipid levels in hyperlipidemia patients during perioperative period. Methods 9 patients with hyperlipidemia treated from January 2014 to December 2015 were selected conveniently. 0 cases. Three groups were randomly divided into three groups, 30 patients in each group were treated with sevoflurane inhalation and maintained in group B with 50ml / 500mg of long chain fatty acids. Group C used 20ml / 200mg of medium-long chain fatty acids to compare the changes of blood lipid levels in each group during perioperative period. Results there were significant changes in serum lipid levels in each group after operation compared with T0. Both LDL and TC values in group C were significantly decreased at T1. The difference was statistically significant (P 0.05). At T2, TG level decreased significantly in group B and C; Conclusion propofol long chain fatty acid has little effect on the changes of blood lipid level in patients with hyperlipidemia and is a safer choice for patients with hyperlipidemia.
【作者单位】： 河南省濮阳市红十字医院麻醉科;
【分类号】：R589.2
【正文快照】： 丙泊酚因其具有麻醉诱导快、术后苏醒迅速和不良反应少,被广泛应用于各种临床麻醉中,并取得良好的麻醉效果。过剂量应用丙泊酚有增加甘油三脂水平、导致肝功能减退,使机体脂肪负荷加重和代谢紊乱的可能,影响血液动力学[1]。该研究通过方便选取2014年1月—2015年12月收治的高脂，

本文编号：1415459