成都地区120例不明原因复发性流产患者证型与体质及相关因素调查

发布时间：2018-01-25 00:23

本文关键词： 不明原因复发性流产证型体质相关因素　出处：《成都中医药大学》2014年硕士论文　论文类型：学位论文

【摘要】：目的：通过调查研究不明原因复发性流产患者的易感体质、常见的辨证分型并了解引起不明原因复发性流产的相关因素,以期为本地区不明原因复发性流产患者的临床治疗提供更多科学依据。方法：遵循流行病学调研方法,设计统一的调研表。筛选符合诊断标准和纳入标准的有复发性流产病史患者共120例为研究组,另选妊娠期间无自然流产史的已育女性60例为对照组。根据中医诊断标准分为：肾气不足证、肾阳亏虚证、肾精亏虚证、脾肾两虚证、气血虚弱证、血热证、血瘀证、肝气郁结证。运用中医体质分类判定标准进行体质判定,通过问卷调查形式收集研究组与对照组基本资料,比较本地区复发性流产患者的体质类型、证型分布规律、体质类型与中医证型之间的相关性,并调查该病的相关因素。结果： (1)研究组与对照组之间年龄分布、教育背景、劳动性质、首次怀孕年龄比较经卡方检验,均为P0.05,无统计学意义。 (2)120例不明原因复发性流产患者自然流产的时间以7～10孕周为多见,占本次调查的61%,其中在同一孕周发生自然流产的有93例,占77.5%。 (3)120例不明原因复发性流产患者的体质类型分布为：气虚质约占28.34%；气郁质约占20.83%；阳虚质约占16.67%。60例对照组中体质类型分布为：平和质约占总调查数的51.67%,余8种偏颇质共占48.33%。 (4)120例不明原因复发性流产患者的中医证型分布为：肾气不足证约占26.7%；肝气郁结证占22.5%；肾阳亏虚证约占11.66%；脾肾两虚证占15.00%。 (5)120例不明原因复发性流产患者的常见体质类型与中医证型相关性经卡方检验,P0.05,有统计学意义。 (6)本次调查研究组与对照组人流方式经卡方检验,P0.05,有统计学意义；两组之间常规人流手术次数经卡方检验,P0.05,无统计学意义；两组之间静脉麻醉下行人流术次数经卡方检验,P0.05,有统计学意义。 (7)本次调查中研究组被动吸烟率为93.3%,对照组被动吸烟率为45%,两组间经卡方检验,P0.05,有统计学意义。 (8)本次调查中研究组患者焦虑情况与自然流产次数经卡方检验,P0.05,有统计学意义；研究组患者抑郁情况与流产次数经卡方检验,P0.05,有统计学意义。结论： (1)不明原因早期复发性流产患者自然流产最多见于7-10孕周；大部分患者自然流产发生在同一孕周。 (2)不明原因复发性流产患者的体质分类以气虚质、气郁质、阳虚质为主,上述三种体质是复发性流产的易感体质。 (3)不明原因复发性流产患者的证型分布以肾气不足证、肝气郁结证、脾肾两虚证、肾阳亏虚证为多见。 (4)不明原因复发性流产患者的常见体质分类与中医证型分布关系较密切,体质决定证型分布。 (5)静脉麻醉下人流术与复发性流产关系密切。 (6)被动吸烟及焦虑、抑郁的精神心理状态也与不明原因复发性流产关系密切。
[Abstract]:Objective: By investigating the susceptible constitution of the patients with recurrent abortion of unknown cause, the common syndrome differentiation and the related factors that caused the recurrent abortion of unknown cause were studied. In order to provide more scientific basis for the clinical treatment of recurrent abortion patients with unknown cause. Methods: According to the method of epidemiological investigation, a unified survey table was designed. 120 patients with history of recurrent abortion were selected as the study group who met the diagnostic criteria and included the criteria. In addition, 60 pregnant women with no history of spontaneous abortion were selected as control group. According to the diagnostic criteria of TCM, they were divided into three groups: deficiency of kidney qi, deficiency of kidney yang, deficiency of kidney essence, deficiency of spleen and kidney, deficiency of qi and blood, and blood heat. Blood stasis syndrome, liver qi stagnation syndrome. Using traditional Chinese medicine constitution classification criteria to determine the constitution, through the form of questionnaire survey to collect the basic information between the study group and the control group, and compare the physical types of recurrent abortion patients in this area. The distribution law of syndromes, the correlation between physique type and TCM syndrome type, and the related factors of the disease were investigated. Results: (1) the age distribution, educational background, nature of labor, age of first pregnancy and age of first pregnancy between the study group and the control group were all P0.05, which had no statistical significance. The time of spontaneous abortion in 120 patients with unexplained recurrent abortion was 710 gestational weeks, accounting for 61% of the survey. 93 cases of spontaneous abortion occurred in the same gestational week. 77.5%. The physical types of 120 patients with recurrent abortion of unknown cause were as follows: Qi deficiency accounted for 28.34%; Qi stagnation accounted for 20.83%; Yang deficiency accounted for 16.67.60 cases in the control group, the distribution of constitution type was as follows: mild quality accounted for 51.67 of the total investigation, and the remaining 8 biased qualities accounted for 48.33. The distribution of TCM syndromes in 120 patients with unexplained recurrent abortion was as follows: the deficiency of kidney qi was about 26.7; Syndrome of stagnation of liver-qi accounted for 22.5B; Deficiency of kidney yang is about 11.66. Spleen and kidney deficiency syndrome accounted for 15.00. The correlation between the common physique types and TCM syndromes in 120 patients with recurrent abortion of unknown cause was statistically significant by chi-square test (P0.05). (6) there was significant difference between the study group and the control group by chi-square test (P0.05). There was no significant difference between the two groups in the number of routine abortion operations by chi-square test (P0.05). The times of artificial abortion under intravenous anesthesia between the two groups were statistically significant by chi-square test (P 0.05). In this investigation, the passive smoking rate in the study group was 93.3g and the passive smoking rate in the control group was 455.There was significant difference between the two groups by chi-square test (P0.05). (8) the anxiety of the patients in the study group and the frequency of spontaneous abortion were statistically significant by chi-square test (P0.05). The depression and the number of miscarriages in the study group were statistically significant by chi-square test (P 0.05). Conclusion: (1) spontaneous abortion occurred most frequently in patients with early recurrent abortion of unknown cause between 7 and 10 weeks of gestation, and most of the patients with spontaneous abortion occurred in the same gestational week. (2) the physique classification of recurrent abortion patients with unknown cause is mainly qi deficiency, qi stagnation and yang deficiency. The above three types of constitution are susceptible to recurrent abortion. The syndrome types of recurrent abortion with unknown cause were deficiency of kidney qi, stagnation of liver qi, deficiency of spleen and kidney, deficiency of kidney yang. 4) the common constitution classification of recurrent abortion patients with unknown cause is closely related to the distribution of TCM syndromes, and constitution determines the distribution of syndromes. 5) artificial abortion under intravenous anesthesia is closely related to recurrent abortion. 6) passive smoking, anxiety and depression were also closely related to recurrent abortion with unknown causes.
【学位授予单位】：成都中医药大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R714.21

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