布托啡诺复合右美托咪定用于颈丛阻滞麻醉下甲状腺手术患者的临床效果

发布时间：2018-01-26 01:05

本文关键词： 布托啡诺右美托咪定颈丛阻滞麻醉甲状腺手术　出处：《中国药物经济学》2016年08期 　论文类型：期刊论文

【摘要】：目的探讨布托啡诺复合右美托咪定治疗颈丛阻滞麻醉下甲状腺手术患者的临床效果。方法选取2014年6月至2015年6月沈阳市红十字会医院收治的甲状腺手术患者64例为研究对象,按随机数字表法分为研究组和对照组,每组32例。两组患者均行颈丛阻滞麻醉,研究组患者在此基础上应用布托啡诺复合右美托咪定,比较两组患者不同时点平均动脉压(MAP)、心率(HR)、警觉/镇静(OAA/S)评分变化、神经阻滞时间及药物安全性等。结果进入手术室时及神经阻滞时两组患者MAP、HR、OAA/S评分比较,差异均无统计学意义(均P0.05);切皮时、分离肿瘤时及手术结束时研究组患者MAP、HR、OAA/S评分与对照组比较,差异均有统计学意义(均P0.05)。研究组患者麻醉阻滞起效时间、阻滞持续时间及镇痛持续时间均优于对照组,差异均有统计学意义(均P0.05);两组患者均无严重不良反应发生。结论布托啡诺复合右美托咪定用于颈丛阻滞麻醉下甲状腺手术应用效果显著,镇痛效果小,血流动力学稳定,不良反应发生率低。
[Abstract]:Objective to investigate the clinical effect of butorphanol combined with dexmetomidine in the treatment of thyroid surgery under cervical plexus block anesthesia. Sixty-four patients undergoing glandular surgery were studied. According to the random number table method, the patients in each group were divided into study group and control group, 32 cases in each group. All patients in both groups were treated with cervical plexus block anesthesia, and the patients in study group were treated with butorphanol combined with dexmetomidine on this basis. The mean arterial pressure (map), heart rate (HRN), alertness / sedation (OAA / S) scores at different time points were compared between the two groups. Results there was no significant difference in MAPHR-OAA / S score between the two groups when entering the operating room and during nerve block (all P 0.05). The OAA / S scores of patients in the study group were compared with those in the control group at the time of skin incision, separation of tumor and the end of operation. All the differences were statistically significant (P 0.05). The onset time of anesthesia block, the duration of block and the duration of analgesia in the study group were better than those in the control group, and the difference was statistically significant (all P 0.05). Conclusion butorphanol combined with dexmetomidine is effective in thyroid surgery under cervical plexus block anesthesia, with little analgesic effect and stable hemodynamics. The incidence of adverse reactions was low.
【作者单位】：沈阳市红十字会医院;
【分类号】：R614
【正文快照】： 甲状腺位于人体颈部,周围神经及血管丰富,甲状腺手术中危险因素较多,采用传统颈丛神经阻滞麻醉术后容易出现声音嘶哑、呛咳、窒息等,不利于患者的术后恢复[1]。甲状腺手术中麻醉方式对手术安全性有直接影响。近年来,颈丛神经阻滞麻醉在甲状腺手术患者中取得了良好的应用效果[2

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