CSI监测下靶控输注依托咪酯在老年高血压全麻诱导中的应用研究

发布时间：2018-02-13 00:11

本文关键词： 麻醉深度指数靶控输注依托咪酯高血压全麻诱导　出处：《白求恩医学杂志》2016年06期 　论文类型：期刊论文

【摘要】：目的研究麻醉深度指数(CSI)监测下靶控输注依托咪酯在老年高血压全麻诱导中应用价值。方法选择在我院行腹腔镜手术的老年高血压患者60例,随机分为两组,各30例。对照组在全麻诱导中应用丙泊酚,而观察组应用依托咪酯。对比两组患者各时间段麻醉深度指数(CSI)、血糖、皮质醇等指标变化情况。结果两组患者麻醉诱导前各项指标均无明显差异(P0.05);观察组与对照组各时间段CSI指数与血糖水平无明显差异(P0.05);观察组诱导前(T0)、气管插管后1min(T1)、即刻拔管后(T2)、拔管后30 min(T3)、拔管后60 min(T4),皮质醇指数均明显低于对照组,差异显著(P0.05)。结论在CSI监测下应用靶控输注依托咪酯对老年高血压患者行全麻诱导,能够有效减少对血流动力学的影响,降低应激反应,提高麻醉的安全性,值得临床推广应用。
[Abstract]:Objective to study the value of target-controlled infusion of etomidate in induction of general anesthesia in elderly hypertensive patients monitored by CSI. Methods 60 elderly hypertensive patients undergoing laparoscopic surgery in our hospital were randomly divided into two groups. 30 cases each. The control group was treated with propofol during general anesthesia induction, while the observation group with etomidate. Results there was no significant difference between the two groups before induction of anesthesia, there was no significant difference in CSI index and blood glucose level between the observation group and the control group, and there was no significant difference in CSI index and blood glucose level between the observation group and the control group before induction and after tracheal intubation. After extubation 30 minutes after extubation and 60 minutes after extubation, the cortisol index was significantly lower than that in the control group. Conclusion Target controlled infusion of etomidate can effectively reduce hemodynamics, reduce stress response and improve the safety of anesthesia in elderly patients with hypertension by using target controlled infusion etomidate under the monitoring of CSI. It is worth popularizing in clinic.
【作者单位】：福建省莆田市第一医院麻醉科;
【分类号】：R614.2

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