小潮气量间歇正压通气对妇科恶性肿瘤患者氧供需平衡的影响

发布时间：2018-02-14 03:05

本文关键词： 小潮气量间歇正压通气妇科肿瘤氧代谢　出处：《广东医学》2015年02期 　论文类型：期刊论文

【摘要】：目的探讨小潮气量间歇正压通气(IPPV)对妇科恶性肿瘤患者机体氧供需平衡的影响。方法选择40例妇科恶性肿瘤手术患者,分为两组,术中分别采用小潮气量和常规潮气量IPPV,于麻醉诱导前、手术开始1、2 h和术毕麻醉苏醒前分别采集桡动脉血和混合静脉血行血气分析及动脉血乳酸浓度测定,并计算动脉血氧含量(Ca O2)、混合静脉血氧含量和氧摄取率(ERO2)。结果两组患者各时点的平均动脉压、心率的比较差异无统计学意义(P0.05),麻醉诱导后两组患者的Cv O2明显升高、ERO2显著下降(P0.01),但两组患者各时点氧代谢相关指标的组间比较差异无统计学意义(P0.05)。结论小潮气量IPPV能很好地维持妇科恶性肿瘤患者手术中的血流动力学稳定,且对机体的氧供需平衡无明显不利影响。
[Abstract]:Objective to investigate the effect of intermittent positive pressure ventilation (IPPVV) with small tidal volume on the balance of oxygen supply and demand in patients with gynecological malignant tumor. Methods 40 patients with gynecologic malignant tumor were selected and divided into two groups. Small tidal volume and conventional tidal volume IPPVwere used respectively during the operation. Radial artery blood and mixed vein blood were collected before anesthesia induction, 1h after operation and before anaesthesia recovery. Blood gas analysis and determination of arterial lactate concentration were performed. The arterial blood oxygen content, mixed venous oxygen content and oxygen uptake rate were calculated. There was no significant difference in heart rate between the two groups (P 0.05). After anesthesia induction, there was a significant increase in CV _ 2 and a significant decrease in ERO _ 2 in the two groups, but there was no significant difference in oxygen metabolism related indexes between the two groups at different time points (P 0.05). Conclusion small tidal volume is not significantly different between the two groups. The dosage of IPPV can maintain the hemodynamic stability of gynecologic malignant tumor patients. And there is no obvious adverse effect on the balance of oxygen supply and demand.
【作者单位】：江西省妇幼保健院麻醉科;
【基金】：江西省自然科学基金资助项目(编号:20132BAB205042)
【分类号】：R737.3

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