口服、肌注与鼻腔内给予咪达唑仑对小儿七氟烷麻醉恢复期躁动的影响

发布时间：2018-02-24 15:06

本文关键词： 给药途径咪达唑仑麻醉躁动　出处：《中国现代药物应用》2016年19期 　论文类型：期刊论文

【摘要】：目的观察口服、肌内注射(肌注)与鼻腔内给予咪达唑仑对小儿七氟烷麻醉恢复期躁动的影响。方法 180例接受手术治疗的患儿,按给药方式不同分为对照组、口服组、肌注组及鼻腔组,每组45例。对照组口服葡萄糖,口服组口服咪达唑仑,肌注组肌内注射咪达唑仑,鼻腔组鼻腔输注咪达唑仑,比较四组不同给药方式的麻醉效果及躁动情况。结果对照组、口服组、肌注组及鼻腔组的麻醉镇静评分(Ramsay)评分分别为(2.13±0.46)、(4.26±1.13)、(5.12±1.01)、(5.20±1.20)分,口服组、肌注组及鼻腔组麻醉Ramsay评分均优于对照组(P0.05);肌注组及鼻腔组麻醉Ramsay评分优于口服组(P0.05)。对照组、口服组、肌注组及鼻腔组的苏醒期躁动评分表(PAED)评分为(18.06±5.63)、(7.21±1.13)、(7.43±1.34)、(7.06±1.41)分,口服组、肌注组及鼻腔组PAED评分均优于对照组(P0.05)。结论口服、肌注与鼻腔内给予咪达唑仑均可减少小儿七氟烷麻醉恢复期躁动,且效果相似,考虑患儿舒适度,建议口服给予咪达唑仑。
[Abstract]:Objective to observe the effects of oral administration, intramuscular injection (intramuscular injection) and nasal administration of midazolam on restlessness during sevoflurane anesthesia in children. Intramuscular injection group and nasal cavity group, each group, 45 cases, control group oral glucose, oral group oral midazolam, intramuscular injection of midazolam, nasal cavity group nasal infusion midazolam, Results the anesthetic sedation scores of the control group, oral group, intramuscular injection group and nasal cavity group were 2.13 卤0.46, 4.26 卤1.13 卤1.01, 5.20 卤1.20 and 5.20 卤1.20, respectively. The anaesthesia Ramsay score of the intramuscular injection group and nasal cavity group was better than that of the control group (P 0.05), the Ramsay score of the intramuscular injection group and the nasal cavity group was better than that of the oral group (P 0.05). The restlessness score of the control group, the intramuscular injection group and the nasal cavity group was 18.06 卤5.63 and 7.21 卤1.1343 卤1.34 + 7.06 卤1.41, respectively. The PAED score of intramuscular injection group and nasal cavity group were better than that of control group (P 0.05). Conclusion midazolam, intramuscular injection and nasal administration can reduce restlessness in convalescent stage of sevoflurane anesthesia in children, and the effect is similar. Considering the comfort of children, midazolam should be given orally.
【作者单位】：解放军第152中心医院;
【分类号】：R726.1

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