右美托咪定用于老年患者无痛纤维肠镜息肉切除术的效果

发布时间：2018-03-15 00:22

本文选题：右美托咪定　切入点：无痛肠镜息肉切除术　出处：《中国老年学杂志》2015年19期 　论文类型：期刊论文

【摘要】：目的探讨老年患者无痛纤维肠镜息肉切除术的麻醉效果及安全性。方法拟行择期无痛纤维肠镜下息肉切除术的老年患者(65~80岁)60例,随机均分为右美托咪定联合丙泊酚组(D组)30例,芬太尼联合丙泊酚组(F组)30例,比较两组术前10 min基础值(T0)、术前5 min(T1)、进镜时(T2)、开始切息肉时(T3)、退镜时(T4)各个时间点的收缩压(SBP)、心率(HR)、血氧饱和度(Sp O2)变化,记录两组各自所用丙泊酚总量、手术时间、苏醒时间、苏醒后视觉模拟评分(VAS)及观察不良反应发生情况。结果 D组丙泊酚使用总量、苏醒时间明显少于F组(P0.05),手术时间、苏醒后VAS无统计学差异(P0.05);T2~T4时D组心率(HR)、收缩压(SBP)显著低于F组,两组HR、SBP显著低于T0(P0.05);T1、T2、T3 F组Sp O2显著低于D组。体动、呼吸抑制的发生率及丙泊酚追加次数D组显著低于F组(P0.05)。结论右美托咪定用于老年患者无痛纤维肠镜息肉切除术,术中呼吸循环稳定,减少丙泊酚用量,缩短苏醒时间,降低不良反应的发生率,用于麻醉更加安全有效。
[Abstract]:Objective to investigate the anesthetic effect and safety of painless fiberoptic polyposis in elderly patients. All patients were randomly divided into two groups: dexmetomidine combined with propofol group (n = 30), fentanyl plus propofol group (n = 30), fentanyl plus propofol group (n = 30). The systolic pressure (SBP), heart rate (HR) and oxygen saturation (SpO _ 2) were compared at 10 min, 5 min, 5 min, T _ 2, T _ 3, T _ 3 and T _ 4, respectively. The total amount of propofol and the time of operation were recorded. Results the total amount of propofol used in group D was less than that in group F (P 0.05). There was no significant difference in VAS after recovery. The heart rate and systolic pressure in group D were significantly lower than those in group F, and that in group D was significantly lower than that in group T _ (0) P _ (0.05) T _ (2) T _ (2) T _ (2) O _ 2 was significantly lower than that in group D (P _ (0) P _ (0.05) T _ (2) T _ (2) T _ (3) T _ (2) T _ (2)). The incidence of respiratory inhibition and the number of propofol supplementation in group D were significantly lower than those in group F (P 0.05). Conclusion dexmetomidine is used in painless fiberoscopic polyposectomy in elderly patients. Reduce the incidence of adverse reactions, for anesthesia is safer and more effective.
【作者单位】：吉林大学中日联谊医院麻醉科;
【分类号】：R614

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