低流量七氟醚吸入麻醉对新生儿肾功能影响的研究

发布时间：2018-03-16 03:16

本文选题：低流量七氟醚　切入点：吸入麻醉　出处：《中国实用医药》2016年31期 　论文类型：期刊论文

【摘要】：目的研究低流量七氟醚吸入麻醉对新生儿肾功能的影响。方法 90例新生儿手术患儿,随机分为研究组和对照组,各45例。研究组患儿使用低流量七氟醚吸入麻醉,对照组患儿使用七氟醚吸入麻醉,观察比较两组患儿在各个时间段(手术前1 d、术后1 h、术后1 d、术后3 d)的肌酐、血清尿素氮含量变化情况。结果研究组手术后1 h肌酐为(54.66±4.39)mmol/L、手术后1 d肌酐为(54.71±4.45)mmol/L,手术后1 h血清尿素氮为(4.23±0.63)mmol/L,手术后1 d血清尿素氮(4.21±0.65)mmol/L,各个时间段的肌酐、血清尿素氮含量比较,差异无统计学意义,(P0.05)。对照组中手术后1 h和1 d的肌酐、血清尿素氮含量均明显较高,接近于正常范围中上限水平,与本组手术前1 d和手术后3 d的含量比较,差异有统计学意义(P0.05)。两组患者手术前1 d和手术后3 d的患儿肌酐、血清尿素氮含量比较,差异无统计学意义(P0.05)。结论对新生儿实施低流量七氟醚吸入麻醉,不会对肾功能造成损害影响,其麻醉效果安全、有效,值得大力推广使用。
[Abstract]:Objective to study the effect of low-flow sevoflurane inhalation anesthesia on renal function of newborns. Methods 90 neonates undergoing operation were randomly divided into study group (n = 45) and control group (n = 45). In the control group, sevoflurane inhalation anesthesia was used to observe and compare the creatinine levels in each time period (1 day before operation, 1 hour after operation, 1 day after operation, 3 days after operation). Results the level of serum urea nitrogen in the study group was 54.66 卤4.39 mmol / L at 1 h after operation, 54.71 卤4.45 mmol / L at 1 day after operation, 4.23 卤0.63 mmolL / L at 1 h after operation, 4.21 卤0.65 mmol / L in serum urea nitrogen at 1 day after operation. There was no significant difference in serum urea nitrogen content between the two groups. In the control group, the creatinine and serum urea nitrogen levels were significantly higher at 1 hour and 1 day after operation than those in the control group, which were close to the upper limit of the normal range. There was significant difference in serum urea nitrogen and creatinine between the two groups 1 day before operation and 3 days after operation. Conclusion the application of low flow sevoflurane inhalation anesthesia to neonates will not affect the renal function, the anesthetic effect is safe and effective, and it is worth popularizing.
【作者单位】：辽宁省沈阳市苏家屯区妇婴医院;

【相似文献】