地佐辛复合丙泊酚在股骨头坏死关节囊针刀松解术中的应用

发布时间：2018-03-19 17:37

本文选题：地佐辛　切入点：芬太尼　出处：《中国医院药学杂志》2015年05期 　论文类型：期刊论文

【摘要】：目的:观察地佐辛复合丙泊酚用于股骨头坏死关节囊针刀松解术的镇痛镇静效果及不良反应。方法:120例择期行股骨头坏死关节囊针刀松解术的患者用数字表法随机分为2组:观察组给予地佐辛联合丙泊酚进行静脉麻醉(D组);对照组给予芬太尼联合丙泊酚进行静脉麻醉(F组)。记录2组术中生命体征、镇痛效果、丙泊酚用量、麻醉恢复时间、呼吸抑制及恶心、呕吐的发生情况。结果:2组镇痛效果优良率均为100%,循环均较稳定,D组呼吸抑制和恶心呕吐发生率均明显低于F组,差异有统计学意义(P0.05)。D组麻醉恢复时间明显短于F组,差异有统计学意义(P0.05)。结论:地佐辛复合丙泊酚用于股骨头坏死关节囊针刀松解术具有血流动力学较平稳、镇痛效果确切、苏醒迅速、麻醉期间呼吸抑制和恶心呕吐发生率低等优点,值得临床推广应用。
[Abstract]:Objective: to observe the analgesic and sedative effects and adverse reactions of dizosin combined with propofol in the treatment of femoral head necrotic joint saccade loosening. Methods: 120 patients with femoral head necrosis were treated with digital table with digital table. The machine was divided into two groups: the observation group was given dizosin combined with propofol for intravenous anesthesia, and the control group was given fentanyl combined with propofol for intravenous anesthesia. Results the effective rate of analgesia, the dosage of propofol, the recovery time of anesthesia, the occurrence of respiratory inhibition, nausea and vomiting were 100, and the incidence of respiratory inhibition and nausea and vomiting in group D were significantly lower than those in group F. The recovery time of anesthesia in group D was significantly shorter than that in group F, and the difference was statistically significant (P 0.05). Conclusion: dizosin combined with propofol has stable hemodynamics and good analgesic effect in the treatment of necrotic joint of femoral head. Rapid recovery, low incidence of respiratory depression and nausea and vomiting during anesthesia are worthy of clinical application.
【作者单位】：武汉市中医医院麻醉科;华中科技大学同济医学院附属同济医院麻醉科;
【分类号】：R614

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