长期饮酒对下腹部手术患者术中麻醉抗药及术后认知功能的影响

发布时间：2018-04-02 02:21

  本文选题：下腹部手术　切入点：长期饮酒　出处：《海南医学院学报》2016年21期

【摘要】：目的:发现长期饮酒对下腹部手术患者术中麻醉抗药及术后认知功能的影响。方法:118例接受下腹部手术的患者纳入研究,分为长期饮酒组43例,对照组75例。对比两组患者的围麻醉期血流动力学指标、应激指标,术后血清氨基酸递质、神经功能指标含量差异。结果:长期饮酒组患者的划皮时(T2)、切口缝合时(T3)血流动力学指标CO、VO2值大于对照组患者,SV值小于对照组患者,应激指标Glu、Cor、AngⅡ、E、NE含量高于对照组患者;长期饮酒组患者的术后血清Glu、Asp、Gly、GABA、Ala、Tau含量高于对照组患者,NSE、S100β、MMP-9含量高于对照组患者,BDNF、ADP含量低于对照组患者。结论:长期饮酒可增加下腹部手术患者的麻醉抗药性,增加术后认知功能障碍发生率。
[Abstract]:Objective: to explore the effect of long-term drinking on anesthesia resistance and postoperative cognitive function in patients undergoing lower abdominal surgery.Methods one hundred and eighty-eight patients undergoing lower abdominal surgery were divided into two groups: chronic drinking group (n = 43) and control group (n = 75).The hemodynamic index, stress index, serum amino acid transmitter and nerve function index were compared between the two groups.Results: in the patients with chronic drinking, the blood flow index COV _ 2 was higher than that in the control group, and the stress index was higher than that in the control group, and the content of Glu-Corn Ang 鈪，

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