乌拉地尔复合艾司洛尔控制性降压在颅内血管瘤介入手术中的应用

发布时间：2018-04-06 00:17

本文选题：乌拉地尔　切入点：艾司洛尔　出处：《河北医学》2016年12期

【摘要】：目的:探讨乌拉地尔复合艾司洛尔控制性降压在颅内血管瘤介入手术中的应用。方法:选取2009年至2015年我院全麻控制性降压下行颅内血管介入手术的患者247例,常规全麻后其中应用乌拉地尔复合艾司洛尔控制性降压的患者127例为研究组,应用硝普钠控制性降压的患者120例为对照组,分别记录两组患者一般资料及手术中平均动脉压、心率、SPO2、Pet CO2等氧合情况,同时选取,对比2组降压方案在颅内血管瘤介入手术中的应用价值和优势。结果:两组患者一般资料比较,差异无统计学意义(P0.05);手术资料对比研究组均优于对照组,其中出血量、血压稳定性评分、异氟醚吸入总量研究组与对照组比较差异有统计学意义(P0.05);2组平均动脉压、血液流变学、心电图、血压监测、呼末二氧化碳分压比较,研究组均优于对照组,差异具有统计学意义(P0.05);手术过程中血压控制稳定性相关因素比较,研究组均优于对照组,但差异均无统计学意义(P0.05)。结论:颅内血管瘤介入手术中在全身麻醉采用乌拉地尔复合艾司洛尔控制性降压较硝普钠控制性降压,对于手术效果及血压控制情况具有明显优势,极具应用价值。
[Abstract]:Objective: to investigate the application of urapidil combined with esmolol in interventional surgery for intracranial hemangioma.Methods: from 2009 to 2015, 247 patients underwent intracranial vascular intervention under general anesthesia and hypotension in our hospital, 127 of whom were treated with urapidil combined with esmolol for the study group.120 patients with controlled hypotension with sodium nitroprusside were used as control group. The general data, mean arterial pressure, heart rate and SPO _ 2P _ et CO2 were recorded in the two groups respectively.To compare the application value and advantage of two groups of hypotension in interventional operation of intracranial hemangioma.Results: there was no significant difference in general data between the two groups, and the operative data in the study group was better than that in the control group, including bleeding volume, blood pressure stability score.There was significant difference between the study group and the control group. The mean arterial pressure, hemorheology, electrocardiogram, blood pressure monitoring and end-exhalation carbon dioxide partial pressure in the study group were better than those in the control group.The difference was statistically significant (P 0.05), and the factors related to the stability of blood pressure control were better in the study group than in the control group, but there was no significant difference between the two groups (P 0.05).Conclusion: the hypotension controlled by urapidil combined with esmolol in interventional operation of intracranial hemangioma is superior to that of sodium nitroprusside in the treatment of intracranial hemangioma.
【作者单位】：河北省涿州市医院麻醉科;
【基金】：河北省保定市科研立项,(编号:15ZF019)
【分类号】：R614

【相似文献】