HIV感染手术患者不同麻醉方式的并发症影响分析

发布时间：2018-04-15 19:22

本文选题：人类免疫缺陷病毒 + 单纯硬膜外麻醉　；参考：《中华医院感染学杂志》2015年02期

【摘要】：目的探讨分析不同麻醉方式对人类免疫缺陷病毒(HIV)感染患者麻醉并发症的影响,为其手术选择适宜的麻醉方式。方法选取2009年6月-2014年6月于医院行手术治疗的78例HIV感染患者,随机将其分为两组,每组各39例,对照组患者行单纯硬膜外麻醉,观察组患者行腰硬联合麻醉,比较两组患者的麻醉效果、不良反应以及T细胞亚群数量变化。结果观察组的患者麻醉起效时间、完善时间分别为(0.82±0.20)、(7.36±1.28)min,对照组分别为(4.33±1.24)、(14.05±2.44)min,观察组低于对照组,两组比较差异有统计学意义;观察组患者麻醉效果优良率100.0%,对照组为92.3%,两组比较差异无统计学意义;观察组患者与对照组的麻醉并发症、术后并发症的发生率与T淋巴细胞亚群变化差异无统计学意义。结论单纯硬膜外麻醉、腰硬联合麻醉效果良好,安全性高,对免疫功能抑制较轻,均可用于HIV感染者的手术,单纯硬膜外麻醉的麻醉并发症、术后并发症的发生率相对较低,但并无明显差异,腰硬联合麻醉起效快,麻醉完善用时短,更具优势。
[Abstract]:Objective to investigate the effects of different anesthetic methods on anesthetic complications in patients with HIV infection and to select appropriate anesthetic methods for their operation.Methods from June 2009 to June 2014, 78 patients with HIV infection were randomly divided into two groups, 39 cases in each group. The patients in the control group were treated with epidural anesthesia alone, and the patients in the observation group were treated with combined spinal-epidural anesthesia.Anaesthesia effects, adverse reactions and changes of T cell subsets were compared between the two groups.Results the onset time and perfect time of anaesthesia in the observation group were 0.82 卤0.20, 7.36 卤1.28 minutes, and in the control group were 4.33 卤1.24 and 14.05 卤2.44 minutes, respectively, which were lower than those in the control group, and there was significant difference between the two groups.The excellent and good rate of anesthetic effect was 100.0g in the observation group and 92.3g in the control group, there was no significant difference between the two groups, but there was no significant difference between the observation group and the control group in the complications of anesthesia, the incidence of postoperative complications and the changes of T lymphocyte subsets.Conclusion simple epidural anesthesia and combined spinal-epidural anesthesia have good effect, high safety and less inhibition of immune function. They can be used in the operation of HIV infected patients. The complications of epidural anesthesia alone are relatively low.But there was no obvious difference. Combined spinal-epidural anaesthesia had the advantages of quick onset, short time to perfect anesthesia.
【作者单位】：永康市妇幼保健院麻醉科;永康市妇幼保健院手术室;
【基金】：浙江省医药卫生基金资助项目(2011KYA100)
【分类号】：R614

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