Narcotrend监测不同麻醉深度对术后认知功能障碍影响的Meta分析

发布时间：2018-04-16 03:24

本文选题：麻醉深度 + Narcotrend监测　；参考：《实用医学杂志》2017年20期

【摘要】：目的研究Narcotrend监测不同麻醉深度下对术后早期认知功能障碍(POCD)发生率的影响。方法系统检索PubMed、OVID、CNKI、CBM、万方数据库、维普数据库等,检索时间限制为建库至2016年12月31日,收集研究Narcotrend监测下不同麻醉深度对术后早期POCD发生率影响的随机对照实验,仔细阅读文献摘和全文,并对其参考文献进行追踪,对纳入文献进行数据提取及质量评价,采用Revman 5.3软件进行分析。结果最终有纳入8篇文献,共包括714例患者。Meta分析结果示:(1)深麻醉状态(NTS E0~E1)术后第1天POCD发生率明显低于常规麻醉状态(NTS D0~D1)(OR=0.21,95%CI0.13~0.35,P0.000 01);(2)深麻醉状态(NTS E1)术后7天POCD发生率明显低于常规麻醉状态(NTSD0)(OR=0.45,95%CI 0.23~0.91,P=0.03);(3)常规麻醉状态中NTS D2术后7 d POCD发生率明显低于NTS D0(OR=0.42,95%CI 0.24~0.71,P=0.001)。结论 Narcotrend监测下深麻醉状态比常规麻醉状态对术后早期POCD发生率低。
[Abstract]:Objective to study the effect of Narcotrend monitoring on the incidence of early postoperative cognitive dysfunction (POCD) under different anesthetic depths.Methods A systematic search was carried out on PubMedus OVIDI CBM, Wanfang database, Wiper database and so on. The search time was limited to the end of December 31, 2016. A randomized controlled trial was conducted to study the effects of different anesthetic depths on the incidence of early postoperative POCD under Narcotrend monitoring.This paper carefully read the abstracts and the full text of the literature, followed up the references, extracted the data and evaluated the quality of the included documents, and analyzed them with the software of Revman 5.3.The results were eventually included in 8 articles,A meta-analysis of 714 patients showed that the incidence of POCD in the first day after operation was significantly lower than that in the normal state of anesthesia. The incidence of POCD was significantly lower than that in the normal state of anesthesia. The incidence of POCD on the 7th day after operation was significantly lower than that in the normal state of anesthesia.The incidence of POCD at 7 days after operation of NTS D2 was significantly lower than that of NTS D _ 0, O, O, O, O, O, 0.42, 95, CI, 0.24, 0.71, P, P, 0. 001.Conclusion the incidence of early postoperative POCD under Narcotrend monitoring is lower than that under conventional anesthesia.
【作者单位】：广州医科大学附属第三医院麻醉科;
【基金】：广东省高等教育学会高等教育科学研究“十三五”规划课题项目(编号:16GYB021) 广州市荔湾区2016科技计划项目(编号:2016080068)
【分类号】：R614

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