两种低流量麻醉药物用于小儿腹腔镜手术的回顾性分析

发布时间：2018-04-16 21:36

本文选题：低流量 + 七氟烷　；参考：《中国药房》2015年26期

【摘要】：目的:评价两种低流量麻醉药用于小儿腹腔镜手术的效果及安全性。方法 :回顾性收集我院2012年1月-2014年12月收治的行腹腔镜手术治疗的72例患儿资料,按照手术前使用麻醉药不同分为试验组和对照组,各36例。根据患儿体质量,试验组患儿使用七氟烷0.1 mg/kg、氧流量0.6 L/min行术前麻醉,对照组患儿使用异氟烷0.1 mg/kg、氧流量0.6 L/min行术前麻醉。比较两组患儿麻醉诱导时间和麻醉前、诱导期、气腹后及手术结束后的动脉压(AP)、心率(HR)、血氧饱和度(Sp O2)、呼气末二氧化碳分压(p Et CO2)及苏醒时间、拔管时间和苏醒后躁动、恶心呕吐等指标。结果 :与麻醉前比较,两组患儿气腹后AP、HR、p Et CO2均显著升高,差异有统计学意义(P0.05),诱导期和气腹后Sp O2无显著变化,差异无统计学意义(P0.05);试验组患儿气腹后HR、AP、p Et CO2均低于对照组,差异有统计学意义(P0.05);试验组患儿术后苏醒时间和拔管时间、躁动所占比例均短于或低于对照组,差异有统计学意义(P0.05)。结论:七氟烷麻醉对患儿机体血压、HR等影响较小,术后苏醒时间与拔管时间较短,副作用小,具有良好的临床效果。
[Abstract]:Objective: to evaluate the efficacy and safety of two low-flow anesthetics in children undergoing laparoscopic surgery.Methods: the data of 72 children who were treated with laparoscopic surgery from January 2012 to December 2014 were collected retrospectively. According to the anesthetic usage before operation, they were divided into experimental group and control group, each with 36 cases.According to the body weight of the patients, the experimental group was anesthetized with sevoflurane 0.1 mg / kg and oxygen flow rate 0.6 L/min. The control group was anesthetized with isoflurane 0.1 mg / kg and oxygen flow 0.6 L/min.The duration of anesthesia induction, induction period, pneumoperitoneum and the end of operation were compared between the two groups. The arterial pressure (APV), heart rate (HRV), blood oxygen saturation (SpO _ 2), end expiratory carbon dioxide partial pressure (Et), recovery time, extubation time and restlessness after recovery were compared between the two groups.Nausea and vomiting.Results: after pneumoperitoneum, there was a significant increase in pEt CO2 after pneumoperitoneum between the two groups (P 0.05), but there was no significant change in SPO 2 during induction and after pneumoperitoneum.There was no significant difference between the two groups (P 0.05), the HRP et CO2 after pneumoperitoneum in the test group was lower than that in the control group (P 0.05), and the recovery time and extubation time in the test group were shorter or lower than those in the control group.The difference was statistically significant (P 0.05).Conclusion: sevoflurane anesthesia has less effect on blood pressure and HR, shorter recovery time and extubation time, less side effect and good clinical effect.
【作者单位】：山东医学高等专科学校附属医院;
【分类号】：R726.1

【参考文献】