穴位针刺对行冠脉狭窄行搭桥手术患者转归及认知功能障碍发生率的影响

发布时间：2018-04-29 21:48

本文选题：针刺 + 冠状动脉搭桥　；参考：《中华中医药学刊》2015年02期

【摘要】：目的:探讨穴位针刺对行冠脉狭窄行搭桥手术患者转归及认知功能障碍发生率的影响。方法:选取我院近年来收治行冠脉狭窄行搭桥手术患者80例,采用随机数字表法分为对照组(40例)和试验组(40例);其中对照组患者行常规静脉吸入复合麻醉,不给予任何电针刺激;试验组患者则在行常规静脉吸入复合麻醉前和搭桥完成后给予电针刺激穴位;比较两组患者围手术期指标,术后认知障碍(POCD)发生率,不同时间点血清S100β蛋白和神经元特异性烯醇化酶(NSE)水平等。结果:两组患者手术时间和麻醉时间比较差异无统计学意义(P0.05);试验组患者机械通气时间、ICU时间及住院时间均显著少于对照组,差异有统计学意义(P0.05);对照组和试验组患者POCD发生率分别为57.50%(23/40),12.50%(5/40);试验组患者POCD发生率显著低于对照组,差异有统计学意义(P0.05);两组患者术前S100β和NSE水平比较差异无统计学意义(P0.05);试验组患者手术完成时、术后6 h及术后12 h S100β和NSE水平均显著低于对照组,差异有统计学意义(P0.05)。结论:穴位针刺用于行冠脉狭窄行搭桥手术患者可有效改善疾病转归,降低认知功能障碍发生风险,具有临床应用价值。
[Abstract]:Objective: to investigate the effect of acupoint acupuncture on the outcome of coronary artery stenosis and the incidence of cognitive impairment. Methods: 80 patients with coronary artery stenosis treated in our hospital in recent years were divided into control group (n = 40) and control group (n = 40) and control group (n = 40). The patients in the test group were treated with electroacupuncture stimulation before routine intravenous inhalation combined anesthesia and after bypass grafting. The perioperative indexes and the incidence of cognitive impairment were compared between the two groups. Serum S 100 尾 protein and neuron specific enolase (NSE) were measured at different time points. Results: there was no significant difference in operation time and anesthesia time between the two groups, and the time of mechanical ventilation, ICU and hospital stay in the experimental group were significantly less than those in the control group. The incidence of POCD in the control group and the experimental group was 57.50% and 12.50%, respectively. The incidence of POCD in the test group was significantly lower than that in the control group. There was no significant difference in the levels of S100 尾 and NSE between the two groups (P 0.05). The levels of S100 尾 and NSE in the test group were significantly lower than those in the control group at 6 hours after operation and 12 hours after operation, and the difference was statistically significant (P 0.05). Conclusion: acupuncture at acupoint can effectively improve the outcome of coronary artery stenosis and reduce the risk of cognitive dysfunction.
【作者单位】：衢州市人民医院;
【分类号】：R246.2

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