全身麻醉应用于剖腹产对新生儿Apgar评分影响的meta分析

发布时间：2018-05-05 03:33

  本文选题：全身麻醉 + 椎管内神经阻滞　； 参考：《安徽医学》2016年07期

【摘要】：目的以剖腹产新生儿Apgar评分为基准,研究全身麻醉对新生儿的影响,探讨能够用于剖腹产的安全、有效、快捷的麻醉方法。方法计算机检索中国学术期刊全文数据库、维普中文科技期刊数据库和万方数据库,收集全身麻醉用于剖腹产的回顾性病例对照研究,试验组为全身麻醉组,对照组为椎管内神经阻滞麻醉组。检索时限的截止日期为2015年10月12日。由2名研究人员按照纳入和排除标准独立筛选文献、评价纳入文献的质量并提取资料,采用RevMan 5.3软件对提取的数据进行统计学分析。结果纳入32个回顾性病例对照研究,均为中文文献,包括试验组1 289例和对照组1 887例,研究对象均为ASA Ⅰ-Ⅱ级的孕产妇。meta分析结果显示:(1)新生儿1 min Apgar评分影响的meta分析显示,全身麻醉与椎管内神经阻滞麻醉的差别有统计学意义(MD=-0.18,P=0.009),椎管内神经阻滞麻醉对剖腹产新生儿1 min Apgar评分的影响更小;(2)新生儿5 min Apgar评分影响的meta分析显示,全身麻醉与椎管内神经阻滞麻醉的差别无统计学意义(MD=0.00,P=1.00);(3)I-D时间的meta分析显示,全身麻醉组的I-D时间较椎管内神经阻滞麻醉组短,全身麻醉具有明显的优势(MD=-9.04,P0.001)。结论全身麻醉与椎管内神经阻滞麻醉对新生儿Apgar评分的影响的差异仍然不明确,但是全身麻醉用于剖腹产手术在娩出胎儿时间上有明显的优势。
[Abstract]:Objective to study the effect of general anesthesia on newborn based on Apgar score of caesarean section and to explore a safe, effective and rapid anesthesia method for caesarean section. Methods the full text database of Chinese academic journals, the database of Chinese scientific and technological journals of Weipu and the database of Wanfang were searched by computer, and a retrospective case-control study of general anesthesia for caesarean section was collected. The experimental group was used as general anesthesia group. The control group was treated with intraspinal nerve block anesthesia. The deadline for retrieval is October 12, 2015. According to the inclusion and exclusion criteria, two researchers independently sifted the literature, evaluated the quality of the included literature and extracted the data, and analyzed the extracted data by RevMan 5.3 software. Results 32 retrospective case-control studies were conducted, all of which were Chinese literature, including 1 289 cases in the trial group and 1 887 cases in the control group. The results of meta-analysis of pregnant women with ASA grade 鈪，

本文编号：1846022