瑞芬太尼和芬太尼用于老年患者麻醉中的临床对比分析

发布时间：2018-05-05 09:31

本文选题：麻醉 + 老年　；参考：《临床医药文献电子杂志》2016年03期

【摘要】：目的比较瑞芬太尼和芬太尼用于老年患者麻醉中的效果。方法选取我院2012年11月~2014年11月收治的老年患者431例,将其随机分为观察组216例与对照组215例。所有患者均进行常规麻醉前准备,观察组给予瑞芬太尼0.1μg/kg,对照组给予芬太尼2.0μg/kg进行麻醉。观察两组患者麻醉后恢复自主呼吸及定向力的时间,苏醒时间以及不良反应发生情况。结果观察组患者恢复自主呼吸、定向力的时间与对照组相比均较短,苏醒较快,差异有统计学意义(P0.05);观察组出现苏醒期躁动、恶心、呕吐、呛咳等不良反应的几率小于对照组,差异有统计学意义(P0.05);观察组麻醉优良率为98.1%,对照组为92.6%,差异有统计学意义(P0.05)。结论同属阿片受体激动剂,与芬太尼相比,瑞芬太尼用于临床麻醉,可明显缩短患者恢复自主呼吸、定向力的时间,麻醉后苏醒较快,出现苏醒期躁动、恶心、呕吐、呛咳等不良反应的几率较小,麻醉的优良率较高,值得临床推广与使用。
[Abstract]:Objective to compare the effect of remifentanil and fentanyl in elderly patients. Methods from November 2012 to November 2014, 431 elderly patients were randomly divided into observation group (216 cases) and control group (215 cases). All patients were prepared for routine anesthesia. The observation group was given remifentanil 0.1 渭 g / kg and the control group was given fentanyl 2.0 渭 g/kg. The recovery time of spontaneous respiration and orientation, recovery time and adverse reaction after anesthesia were observed. Results the time of recovery of spontaneous respiration in the observation group was shorter than that in the control group, and the recovery rate of the patients in the observation group was shorter than that in the control group, and the difference was statistically significant (P 0.05), and the incidence of adverse reactions such as restlessness, nausea, vomiting and cough in the observation group was less than that in the control group. The difference was statistically significant (P 0.05), the excellent and good rate of anesthesia in the observation group was 98.1 and that in the control group was 92.6.The difference was statistically significant (P 0.05). Conclusion compared with fentanyl, remifentanil can significantly shorten the time of recovery of spontaneous respiration and orientation after anaesthesia, and remifentanil can induce restlessness, nausea and vomiting during anaesthesia. The adverse reactions such as cough are less and the excellent and good rate of anesthesia is higher, so it is worth popularizing and using in clinic.
【作者单位】：深州市医院麻醉科;深州市医院检验科;深州市医院外科;
【分类号】：R614

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