地氟醚与七氟醚用于肥胖患者妇科腹腔镜手术麻醉效果的比较

发布时间：2018-05-05 15:12

本文选题：地氟醚 + 七氟醚　；参考：《广东医学》2017年13期

【摘要】：目的比较地氟醚与七氟醚用于肥胖患者妇科腹腔镜手术麻醉的效果。方法选取行腹腔镜妇科手术的肥胖患者60例,随机分配至地氟醚组和七氟醚组,每组30例。气管插管后分别以地氟醚和七氟醚维持麻醉。比较两组患者自停用吸入麻醉药开始至第1次自主呼吸的时间、呼之睁眼时间、拔管时间、指令应答名字时间、转出麻醉复苏室(PACU)时间;比较两组患者在术后不同时刻平均动脉压(MAP)、心率(HR)和疼痛视觉模拟评分(VAS)。比较患者术后不良事件及躁动发生情况。结果地氟醚组患者停药后第1次自主呼吸的时间、呼之睁眼时间、拔管时间、指令应答名字时间、转出PACU时间均短于七氟醚组(P0.001),地氟醚组发生恶心呕吐事件的频率高于七氟醚组(43.3%vs 10.0%,P=0.001)。两组患者在血液动力学变化、疼痛评分和躁动发生情况均差异无统计学意义(P0.05)。结论与七氟醚相比,应用地氟醚吸入维持麻醉的肥胖患者妇科腹腔镜术后苏醒时间明显缩短,但恶心呕吐的发生率较高。
[Abstract]:Objective to compare the anesthetic effect of desflurane and sevoflurane in obese patients undergoing gynecologic laparoscopic surgery. Methods 60 obese patients undergoing laparoscopic gynecologic surgery were randomly assigned to desflurane group and sevoflurane group with 30 cases in each group. Anesthesia was maintained with desflurane and sevoflurane after tracheal intubation. The time from discontinuation of inhaled anesthetics to the first time of spontaneous respiration, the time of eye opening, extubation, the time of command answering name, and the time of transferring out of the anaesthesia resuscitation chamber were compared between the two groups. The mean arterial pressure (map), heart rate (HR) and visual analogue score (VASA) were compared between the two groups at different time after operation. Adverse events and restlessness were compared. Results in the desflurane group, the time of the first time of spontaneous respiration, the time of opening eyes, the time of extubation, the time of command answering name, The frequency of nausea and vomiting in desflurane group was higher than that in sevoflurane group (43.3 vs 10.0). There was no significant difference in hemodynamics, pain score and restlessness between the two groups (P 0.05). Conclusion compared with sevoflurane, desflurane inhaled maintenance anesthesia in obese patients after gynecologic laparoscopy significantly shortened the recovery time, but the incidence of nausea and vomiting was higher than that of sevoflurane.
【作者单位】：佛山市妇幼保健院麻醉科;
【分类号】：R614

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