不同剂量右美托咪定对腹部手术患者血糖浓度和心率的影响

发布时间：2018-05-06 05:12

本文选题：麻醉 + 全身　；参考：《重庆医学》2015年09期

【摘要】：目的探讨不同剂量的右美托咪定对腹部手术患者血糖浓度和心率的影响,为临床麻醉合理用药提供依据。方法选取该院2013年1~9月择期腹部手术行全身麻醉患者80例,分为生理盐水对照组(S组)、右美托咪定0.6μg/kg剂量组(D1组)、0.8μg/kg剂量组(D2组)和1μg/kg剂量组(D3组),每组各20例。检测患者插管后30min、手术后1h和手术后6h的血糖浓度;监测并记录患者麻醉诱导前、麻醉诱导后、插管后、手术15、30、45、60、75、90、105、120min和术后15min的心率变化。结果手术后1h,D2组和D3组患者血糖浓度显著低于S组(P0.05),插管后30min和手术后6h,各组比较差异均无统计学意义(P0.05)。与S组患者同一时间的心率比较,D2组患者在插管后60、75、90min心率显著降低(P0.05),D3组在整个手术期间均显著性降低(P0.05)。结论右美托咪定能够缓解患者围术期应激反应的血糖浓度和心率变化。
[Abstract]:Objective to investigate the effects of dexmetidine on blood glucose and heart rate in patients undergoing abdominal surgery. Methods from January to September 2013, 80 patients undergoing general anesthesia were divided into normal saline control group (S group), dexmetomidine 0.6 渭 g/kg group (0. 8 渭 g/kg) group (D 2 group) and 1 渭 g/kg dose group (20 cases in each group). The blood glucose concentrations were measured 30 minutes after intubation, 1 hour after operation and 6 hours after operation, and the changes of heart rate before anesthesia induction, after anesthesia induction and after intubation were monitored and recorded. Results the blood glucose concentration in D 2 group and D 3 group was significantly lower than that in S group at 1 h after operation, and there was no significant difference between the two groups in 30min after intubation and at 6 h after operation (P 0.05). The heart rate of D 2 group was significantly lower than that of S group at the same time. The heart rate of D 2 group was significantly lower than that of D 2 group during the whole operation. Conclusion dexmetomidine can relieve the changes of blood glucose and heart rate in perioperative stress response.
【作者单位】：枣庄矿业集团中心医院手术麻醉科;
【分类号】：R614

【共引文献】