硬膜外麻醉对不同年龄糖尿病患者血液流变学、血浆胰岛素及血糖水平的影响

发布时间：2018-05-08 11:14

本文选题：硬膜外麻醉 + 糖尿病　；参考：《中国老年学杂志》2017年01期

【摘要】：目的研究硬膜外麻醉对老年糖尿病患者血液流变学、血浆胰岛素水平及血糖水平的影响。方法 2014年6月至2015年6月该院收治的糖尿病患者按年龄分为老年组和非老年组,每组40例,均实施硬膜外麻醉,比较相同麻醉方式对两组患者血液流变学指标的影响;分别对两组患者在进行麻醉之前、手术进行30 min、手术结束时、术后4 h抽取的静脉血进行血浆胰岛素及血糖测定。结果两组患者麻醉后全血低切和高切黏度、低切和高切还原黏度均比麻醉之前低;老年组患者麻醉后全血高切黏度比非老年组低。两组患者麻醉前胰岛素水平及血糖水平无统计学差异(P0.05);手术30 min、术毕、术后4 h空腹血浆胰岛素血糖水平较术前升高(P0.05),与非老年组相比老年组增高较明显。结论对糖尿病患者采用硬膜外麻醉方式可以使血液流变学相关参数降低,血浆胰岛素水平及血糖水平保持相对稳定,对脏器的血液灌注有明显的益处,其中对老年患者效果更加显著。
[Abstract]:Objective to study the effects of epidural anesthesia on hemorheology, plasma insulin level and blood glucose level in elderly diabetic patients. Methods from June 2014 to June 2015, diabetic patients in our hospital were divided into two groups according to their age. 40 cases in each group were treated with epidural anesthesia. The effects of the same anesthesia on hemorheology were compared between the two groups. The plasma insulin and blood glucose were measured 4 hours after the operation and 30 minutes before anesthesia. Results the whole blood low shear viscosity and high shear viscosity, low shear and high shear reduction viscosity were lower in the two groups than before, and the whole blood high shear viscosity in the elderly group was lower than that in the non-elderly group after anesthesia. There was no significant difference in insulin level and blood glucose level between the two groups before anesthesia (P 0.05), but the fasting plasma insulin and blood glucose level in 30 min, 4 h after operation was higher than that before operation (P 0.05), which was significantly higher than that in the non-elderly group. Conclusion epidural anesthesia can decrease the parameters of hemorheology and keep the level of plasma insulin and blood sugar stable, which is beneficial to the blood perfusion of viscera. Among them, the effect on the elderly patients is more remarkable.
【作者单位】：厦门大学附属第一医院麻醉科;
【基金】：福建省卫生厅青年科研课题资助计划(2012-2-78)
【分类号】：R614

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