地佐辛不同用药方式对剖宫产术患者麻醉后寒战的预防效果研究

发布时间：2018-05-19 06:44

本文选题：地佐辛 + 不同用药方式　；参考：《河北医学》2016年06期

【摘要】：目的:研究地佐辛不同用药方式对剖宫产术患者寒战的预防效果。方法:将剖宫产手术的产妇135例作为研究对象,根据简单数字随机表法将产妇分成A、B、C三组各45例。麻醉且胎儿取出后,预处理:A组给予3m L的生理盐水静注;B组给予地佐辛静注,剂量为0.1mg/kg;C组给予地佐辛肌注,剂量为0.1mg/kg。再给予寒战预防处理:A组静注0.1mg/kg的地佐辛,B、C两组分别给予0.05mg/kg的地佐辛静注。对比各组麻醉后的寒战反应情况,产妇的Ramsay镇静评分,以及围术期的相关指标(BMP、HR、RR)。结果:B组寒战反应发生率为11.11%,显著低于A组的51.11%及C组的28.89%,C组寒战反应发生率亦显著低于A组,B组Ramsay镇静评分显著高于A组及C组,差异有统计学意义(P0.05)。各组在术前及术后的MBP、HR及RR的水平相比,差异均无统计学意义(P0.05)。B组和C组术中的HR及RR水平显著低于A组,差异有统计学意义(P0.05)。结论:静脉注射或肌肉注射地佐辛可有效预防剖宫产术患者寒战,但静脉注射的预防效果更佳,值得临床重视。
[Abstract]:Objective: To study the effect of different use of digoxin on the chills of caesarean section patients. Methods: 135 cases of caesarean section were taken as the research object. According to the simple digital random table, the parturients were divided into groups of A, B, and C three. After the anesthesia and fetuses were taken out, the A group was given 3M L saline infusion; group B was given to digoxin. Intravenous injection, dose of 0.1mg/kg, group C injected with zocin, dose of 0.1mg/kg., and chill prevention treatment: A group 0.1mg/kg of 0.1mg/kg, B, C two groups were given 0.05mg/kg's Zo zoxine injection respectively. Compared with each group after anaesthesia, the shivering response, the parturient's Ramsay sedation score, and the perioperative related indexes (BMP, HR, RR). The incidence of chill reaction was 11.11%, significantly lower than group 51.11% in A and 28.89% in group C, and in group C, the incidence of chill reaction was also significantly lower than that in group A. The Ramsay sedation score in group B was significantly higher than that in group A and C group, the difference was statistically significant (P0.05). There was no significant difference between the groups of MBP, HR and RR before and after the operation. The level of HR and RR in the operation was significantly lower than that in group A, and the difference was statistically significant (P0.05). Conclusion: intravenous or intramuscular injection of dezoxine can effectively prevent caesarean section, but the effect of intravenous injection is better. It is worthy of clinical attention.
【作者单位】：江苏省常州中医院麻醉科;
【基金】：江苏省自然科学基金资助项目(编号:BK2008232)
【分类号】：R614

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