全麻下不同给药顺序对舒芬太尼麻醉引发呛咳的影响

发布时间：2018-05-24 22:15

本文选题：全麻 + 给药顺序　；参考：《中国医药指南》2016年10期

【摘要】：目的分析探讨全麻下不同给药顺序对舒芬太尼麻醉引发呛咳的影响效果。方法选取在我院进行择期全麻的72例患者作为研究对象,将其随机均分为A组、B组及C组,三组患者在麻醉时均使用丙泊酚、舒芬太尼及顺式阿曲库铵,A组的给药顺序为丙泊酚2.0 mg/kg、舒芬太尼0.6μg/kg、顺式阿曲库铵0.15 mg/kg,B组的为丙泊酚2.0 mg/kg、顺式阿曲库铵37.5μg/kg、舒芬太尼0.6μg/kg、顺式阿曲库铵112.5μg/kg,C组的则为丙泊酚2.0 mg/kg、顺式阿曲库铵0.15 mg/kg、舒芬太尼0.6μg/kg。观察并分析对比三组患者的麻醉前后的血流动力学变化情况及给药后呛咳发生情况。结果三组患者诱导前后的血流动力学不会发生明显变化,且C组的呛咳发生明显小于A、B组,且差异比较有统计学意义(P0.05)。结论按照丙泊酚、顺式阿曲库铵、舒芬太尼的顺序来给药能够有效减轻患者的呛咳反应,且不会对患者的血流动力学产生影响,具有在临床上深入推广的价值。
[Abstract]:Objective to study the effect of different administration order on cough induced by sufentanil anesthesia. Methods Seventy-two patients undergoing elective general anesthesia in our hospital were randomly divided into group A (group B) and group C (group C). All three groups were treated with propofol during anesthesia. The order of administration of sufentanil and cis atracurium was 2.0 mg / kg propofol, 0.6 渭 g / kg sufentanil, 2.0 mg / kg propofol, 37.5 渭 g / kg cis atracurium, 0.6 渭 g / kg sufentanil and 112.5 渭 g / kg cis atracurium, respectively. Phenol 2.0 mg / kg, cis atracurium 0.15 mg / kg, sufentanil 0.6 渭 g / kg. The hemodynamic changes before and after anesthesia and the occurrence of cough after administration were observed and analyzed. Results there was no significant change in hemodynamics before and after induction, and the incidence of cough in group C was significantly lower than that in group A and B, and the difference was statistically significant (P 0.05). Conclusion according to the sequence of propofol, cis-atracurium and sufentanil, it can effectively reduce the cough response of patients, and has no effect on hemodynamics.
【作者单位】：湖南省湘阴县人民医院麻醉科;
【分类号】：R614.2

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