乙肝肝硬化脾切除术患者术后使用参附注射液对全麻苏醒质量的影响

发布时间：2018-05-25 22:40

本文选题：脾切除术 + 参附注射液　；参考：《实用医学杂志》2015年13期

【摘要】：目的:观察参附注射液对肝功能失代偿脾切除术患者术后全身麻醉苏醒的影响。方法:选取40例乙肝肝硬化、肝功能失代偿期在全麻下行脾切除的患者,ASAⅡ~Ⅲ级,随机分为两组:参附组(SFI组)及对照组(C组)。两组患者术毕麻醉未醒及无自主呼吸入麻醉后监护室(PACU)后,SFI组在患者入PACU后于10 min内静脉输注参附注射液1 m L/kg,对照组则输注等量生理盐水。记录两组患者的睁眼时间、拔管时间、PACU停留时间,并记录用药前和用药后5、15、45 min时的心率(HR)、平均动脉压(MAP)。同时记录各组患者的烦躁发生率。结果:与C组比较,SFI组的睁眼时间、拔管时间、PACU停留时间差异无显著性(P0.05);同输注前比较,SFI及生理盐水输注后5、15、45 min的HR及MAP差异无显著性(P0.05)。但SFI组患者的烦躁发生率明显低于C组(P0.05)。结论 :单纯参附注射液能减少肝功能失代偿行脾切除术患者的苏醒期烦躁发生率。
[Abstract]:Objective: to observe the effect of Shenfu injection on recovery of general anesthesia after decompensated splenectomy. Methods: forty patients with liver cirrhosis undergoing splenectomy under general anesthesia during decompensation were randomly divided into two groups: Shenfu group (SFI group) and control group (C group). Patients in both groups were given 1 mL / kg Shenfu injection in 10 min after PACU, and the control group was given the same amount of normal saline. The eye opening time, extubation time and PACU stay time were recorded in both groups. Heart rate and mean arterial pressure were recorded before and after 5 ~ 15 ~ 45 min. At the same time, the incidence of irritability in each group was recorded. Results: there was no significant difference in eye opening time, extubation time and PACU residence time between group C and group C, but there was no significant difference in HR and MAP between group C and group C (P 0.05). But the incidence of irritability in SFI group was significantly lower than that in C group (P 0.05). Conclusion: Shenfu injection alone can reduce the incidence of agitation in patients with liver decompensation and splenectomy.
【作者单位】：南方医科大学第一临床学院附属广州军区广州总医院麻醉科全军临床麻醉中心;
【分类号】：R614.2

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