丙泊酚复合氯胺酮静脉麻醉用于先天性心脏病患儿介入治疗的效果观察

发布时间：2018-05-29 22:09

本文选题：丙泊酚 + 氯胺酮　；参考：《中国药房》2015年03期

【摘要】：目的:观察丙泊酚复合氯胺酮静脉麻醉用于先天性心脏病(简称先心病)患儿介入治疗的效果及安全性。方法:选取我院收治的70例择期行介入治疗的先心病室间隔缺损患儿,随机均分为丙泊酚复合氯胺酮静脉麻醉组(PK组)和氯胺酮静脉麻醉组(K组),均采用微量泵静脉持续输注。比较两组患儿血流动力学指标、手术时间、苏醒时间、并发症及不良反应发生率。结果:PK组患儿手术期间平均动脉压(MAP)和心率(HR)均未见显著变化(P0.05),而K组患儿手术期间MAP和HR均较PK组和同组基础麻醉后显著增高,差异均有统计学意义(P0.05)。PK组患儿苏醒时间显著短于K组,差异均有统计学意义(P0.01);术中体动发生率显著低于K组(P0.05)。结论:丙泊酚复合氯胺酮静脉麻醉相比单用氯胺酮静脉麻醉能明显减轻先心病患儿介入治疗中的应激反应,减少体动的发生,且术后苏醒快。
[Abstract]:Objective: to observe the efficacy and safety of intravenous anesthesia with propofol and ketamine in children with congenital heart disease. Methods: 70 children with ventricular septal defect were randomly divided into propofol and ketamine intravenous anesthesia group (PK group) and ketamine intravenous anesthesia group (K group). Hemodynamic indexes, operation time, recovery time, complications and adverse reactions were compared between the two groups. Results there were no significant changes in mean arterial pressure (MAPP) and heart rate (HR) during operation in group K, but MAP and HR in group K were significantly higher than those in group K after basic anesthesia. The difference was statistically significant in the recovery time of children in P0.05U .PK group than that in group K (P 0.01), and the incidence of body movement in group K was significantly lower than that in group K (P 0.05). Conclusion: propofol combined with ketamine intravenous anesthesia can significantly reduce stress response and body movement in children with congenital heart disease compared with ketamine intravenous anesthesia alone.
【作者单位】：中山市中医院麻醉科;
【分类号】：R726.1

【参考文献】