右美托咪定对七氟烷麻醉下不停跳冠状动脉旁路移植术患者血流动力学的影响

发布时间：2018-06-08 21:18

  本文选题：右美托咪定 + 七氟烷麻醉　； 参考：《中国医院用药评价与分析》2016年07期

【摘要】：目的:探讨右美托咪定对七氟烷麻醉下不停跳冠状动脉旁路移植术患者血流动力学的影响。方法:选取2013年10月—2014年11月郑州市中医院收治的行不停跳冠状动脉旁路移植术的患者112例,以随机数字表法分为观察组和对照组各56例。对照组给予0.9%氯化钠注射液,观察组给予右美托咪定。观察2组患者桡动脉穿刺完毕(T_0)、气管插管完毕(T_1)、劈开胸骨(T_2)、搭前降支(T_3)、头低位搭后降支(T_4)、术毕(T_5)时各项指标情况。结果:观察组患者在T_1、T_2、T_4、T_5时的平均动脉压均明显低于对照组,差异均有统计学意义(P0.05);观察组患者在T_1、T_2、T_4、T_5时的心率均明显低于对照组,差异均有统计学意义(P0.05)。结论:在七氟烷麻醉下不停跳冠状动脉旁路移植术中持续泵注右美托咪定,疗效较好,应激反应减轻,平均动脉压降低,改善心率,值得推广。
[Abstract]:Aim: to investigate the effect of dexmetomidine on hemodynamics in patients undergoing coronary artery bypass grafting (CABG) under sevoflurane anesthesia. Methods: 112 patients treated with coronary artery bypass grafting in Zhengzhou traditional Chinese Medicine Hospital from October 2013 to November 2014 were randomly divided into observation group (n = 56) and control group (n = 56). The control group was given 0.9% sodium chloride injection, and the observation group was given dexmetomidine. The indexes of the two groups were observed at the end of the puncture of radial artery, the tipping of T _ (1), the splitting of sternum T _ (2), the establishment of anterior descending branch (T _ (3), the first and posterior branch of T _ (4), and the end of operation (T _ (5). Results: the mean arterial pressure of the patients in the observation group was significantly lower than that in the control group at T _ 1 / T _ 2 / T _ 4 / T _ 5, and the heart rate in the observation group was significantly lower than that in the control group at the time of T _ 1 / T _ 2 / T _ 4 / T _ 5, and the difference was statistically significant (P 0.05). Conclusion: continuous pump of dexmetomidine in coronary artery bypass grafting under sevoflurane anesthesia has better effect, less stress response, lower mean arterial pressure, improved heart rate and is worth popularizing.
【作者单位】： 郑州市中医院麻醉科;
【分类号】：R614
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本文编号：1997157