右美托咪定用于气管异物取出术麻醉效果评价

发布时间：2018-07-24 11:20

【摘要】：目的:探讨右美托咪定用于小儿气管异物取出术麻醉效果。方法:选择本院急诊行气管异物取出术的患儿50例,随机分为对照组和试验组,每组25例,分别在全麻诱导前10 min内静脉输注氯化钠溶液或右美托咪定(0.5μg/kg)。术中用丙泊酚和瑞芬太尼诱导和维持麻醉。记录入手术室时(T0)、置支气管镜前1 min(T1)、置支气管镜时(T2)、置支气管镜后1 min(T3)、退支气管镜时(T4)的HR、BP和Sp O2,术中丙泊酚和瑞芬太尼用量,术后呛咳、躁动、呕吐等的发生例数和苏醒时间等。结果:两组间各时间点HR、MAP、Sp O2比较无差异(P0.05)。与对照组比较,试验组手术过程中丙泊酚和瑞芬太尼用量减少(P0.05),术后呛咳、躁动、呕吐等的发生例数减少(P0.05)。两组苏醒时间比较差异无统计学意义(P0.05)。结论:在气管异物取出术中,右美托咪定能减少丙泊酚和瑞芬太尼的用量,术后苏醒质量好。
[Abstract]:Objective: to investigate the anesthetic effect of dexmetomidine in tracheal foreign body removal in children. Methods: 50 children with trachea foreign body extraction were randomly divided into control group and experimental group, 25 patients in each group were injected intravenously with sodium chloride solution or dexmetomidine (0.5 渭 g/kg) 10 min before induction of general anesthesia. Anesthesia was induced and maintained with propofol and remifentanil. The dosages of propofol and remifentanil were recorded during operation room (T0), 1 min before bronchoscopy (T1), 1 min after bronchoscopy (T2), 1 min after bronchoscopy (T3), T4, the dosage of propofol and remifentanil during operation. The number of cases of vomiting, etc., and the time of recovery, etc. Results: there was no difference between the two groups (P0.05). Compared with the control group, the dosage of propofol and remifentanil decreased (P0.05), postoperative cough, restlessness, vomiting and other cases decreased (P0.05). There was no significant difference in recovery time between the two groups (P0.05). Conclusion: dexmetomidine can reduce the dosage of propofol and remifentanil in the removal of tracheal foreign body.
【作者单位】：广西医科大学第一附属医院;
【基金】：广西壮族自治区卫生厅自筹经费科研课题(Z2013008)
【分类号】：R614

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