不同浓度七氟醚对老年冠心病患者麻醉诱导期心率变异性的影响
发布时间:2018-07-31 09:07
【摘要】:目的探讨七氟醚对老年冠心病患者在全麻诱导期心率变异性(HRV)的影响。方法 40例择期行上腹部手术老年冠心病患者,美国麻醉医生协会(ASA)Ⅱ~Ⅲ级。随机分为低浓度组和高浓度组,每组20例。麻醉诱导开始时,缓慢静脉推注芬太尼3μg/kg,吸入6 L/min氧气及七氟醚,维持七氟醚的呼气末浓度在预定值(低浓度组为2.0 Vol%,高浓度组为4.0 Vol%),当意识和睫毛反射消失后,静注维库溴胺0.1 mg/kg,行气管插管。记录麻醉前基础值及诱导后5、10、15、20 min的收缩压(SBP)、舒张压(DBP)、心率(HR)、心率变异性(HRV),并记录各组肌僵、呛咳、低血压等副反应的发生情况。结果 2组患者的SBP、DBP在诱导后5、10 min显著下降(P0.05),高浓度组下降较低浓度组明显(P0.05),其后患者的血压渐趋平稳,2组心率无显著变化(P0.05)。在麻醉诱导中,2组低频(LF)和低频/高频(LF/HF)逐渐降低,而HF均没有明显的变化,其中高浓度组比低浓度组对HRV各参数的影响都较明显。结论老年冠心病患者用七氟醚吸入麻醉诱导主要抑制心脏交感神经活性,并呈剂量依赖性,对血流动力学影响较轻,诱导相对平稳,适合老年冠心病患者的麻醉诱导。
[Abstract]:Objective to investigate the effect of sevoflurane on heart rate variability (HRV) in elderly patients with coronary heart disease during induction of general anesthesia. Methods 40 elderly patients with coronary heart disease undergoing epigastric surgery were enrolled in this study. The American Association of Anesthesiologists, (ASA) 鈪,
本文编号:2155101
[Abstract]:Objective to investigate the effect of sevoflurane on heart rate variability (HRV) in elderly patients with coronary heart disease during induction of general anesthesia. Methods 40 elderly patients with coronary heart disease undergoing epigastric surgery were enrolled in this study. The American Association of Anesthesiologists, (ASA) 鈪,
本文编号:2155101
本文链接:https://www.wllwen.com/yixuelunwen/mazuiyixuelunwen/2155101.html
最近更新
教材专著