手术麻醉患者呼吸道感染的相关性研究

发布时间：2018-07-31 10:16

【摘要】：目的探讨呼吸道感染与麻醉相关因素,为临床应用提供理论依据。方法选取2011年10月-2014年1月手术麻醉患者570例,基于患者是否发生感染分为感染组320例和非感染组250例,对气管插管麻醉相关因素实施相关性分析,分析因素包括喉镜消毒方式、过滤器类型、抗菌药物使用、插管等;采用SPSS16.0软件进行统计分析,计数资料采取χ2检验。结果盲深插管、拔管延迟且3h为感染非相关因素,OR值均2.00,对比差异无统计学意义;感染相关性因素为喉镜消毒方式(OR=3.56,χ2=37.51)、过滤器类型(OR=4.21,χ2=44.58)、抗菌药物使用(OR=2.11,χ2=14.15)、插管过深(OR=2.14,χ2=13.73)、插管不熟练(OR=2.10,χ2=15.08)、拔管指征不完全(OR=2.21,χ2=24.97)、拔管延迟且3h(OR=3.41,χ2=34.89),对比差异有统计学意义;感染组患者共培养分离出395株病原菌,以革兰阴性菌为主,占58.61%。结论引发气管插管麻醉患者呼吸道发生感染的相关危险因素较多,需要引起注意,针对性预防,降低感染率。
[Abstract]:Objective to explore the related factors of respiratory tract infection and anesthesia and to provide theoretical basis for clinical application. Methods 570 patients undergoing anesthesia from October 2011 to January 2014 were divided into infected group (320 cases) and non-infected group (250 cases). The factors included laryngoscope disinfection, filter type, antimicrobial use, intubation and so on. Statistical analysis was carried out by SPSS16.0 software and 蠂 2 test was used to count the data. Results in deep blind intubation, delayed extubation and 3 hours of delayed extubation were all non-related factors of infection (OR = 2.00), and there was no significant difference between the two groups. The factors associated with infection were laryngoscope disinfection (OR 3.56, 蠂 2 + 37.51), filter type (OR 4.21, 蠂 2 + 44.58), antibiotic use (OR2.11, 蠂 2 + 14.15), too deep intubation (OR2.14, 蠂 2 13.73), unskilled intubation (OR 2.10, 蠂 215.08), incomplete extubation indication (OR2.21, 蠂 224.97), delayed extubation and 3h (ORT 3.41, 蠂 2 44.89). The difference was statistically significant. 395 strains of pathogenic bacteria were isolated from the infected group, mainly Gram-negative bacteria (58.61%). Conclusion there are many risk factors related to respiratory tract infection in patients undergoing tracheal intubation anesthesia.
【作者单位】：青海大学附属医院麻醉科;
【基金】：教育部高校博士点基金资助项目(200802481094)
【分类号】：R614

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