经可弯曲支气管镜介入治疗恶性肿瘤致中央气道狭窄并呼吸衰竭

发布时间：2018-08-28 13:37

【摘要】：目的 :探讨经可弯曲支气管镜介入治疗恶性肿瘤致中央气道狭窄并呼吸衰竭的可行性、有效性及安全性。方法 :回顾性分析南京医科大学第一附属医院2010年2月—2013年5月喉罩通气全身麻醉下经可弯曲支气管镜介入治疗的12例恶性肿瘤致中央气道狭窄并呼吸衰竭患者的临床资料、介入治疗结果。介入治疗技术包括应用高频电灼术、氩等离子体凝固术、冷冻消融、球囊扩张及自膨胀金属支架置入等。结果:12例患者,男6例,女6例,平均年龄(58±9)岁。12例患者经可弯曲支气管镜介入治疗后气促指数明显改善(P0.01),11例患者呼吸衰竭得到纠正,1例患者术后气管插管行机械通气治疗,3 d后拔管并顺利撤除呼吸机,有效率为100%。无1例患者出现大出血、心脏骤停等严重并发症。结论:经可弯曲支气管镜介入治疗恶性肿瘤致中央气道狭窄并呼吸衰竭可行、安全及有效,值得临床应用。
[Abstract]:Objective: to evaluate the feasibility, efficacy and safety of bendable bronchoscopy in the treatment of central airway stenosis and respiratory failure caused by malignant tumor. Methods: a retrospective analysis of 12 patients with central airway stenosis and respiratory failure caused by malignant tumors under general anesthesia with laryngeal mask ventilation was performed in the first affiliated Hospital of Nanjing Medical University from February 2010 to May 2013. Clinical data of patients, The outcome of interventional therapy. Interventional therapy includes high frequency electrocautery, argon plasma coagulation, cryotherapy, balloon dilatation and self-expanding metal stent implantation. Results of 12 patients, 6 were male and 6 female. The mean age of 12 patients was (58 卤9) years old. After bendable bronchoscopic intervention therapy, the respiratory index of 11 patients with respiratory failure was significantly improved (P0.01). One patient received tracheal intubation after 3 days of mechanical ventilation and successfully removed the ventilator. The effective rate is 100. There were no severe complications such as massive hemorrhage, cardiac arrest and so on. Conclusion: it is feasible, safe and effective to treat central airway stenosis and respiratory failure caused by malignant tumor by bendable bronchoscopy.
【作者单位】：南京医科大学第一附属医院呼吸科;
【基金】：江苏省呼吸病临床医学研究中心(BL2012012)
【分类号】：R730.5

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