右美托咪啶不同镇静深度下记忆加工分离程序分析

发布时间：2018-09-09 16:54

【摘要】：目的对比右美托咪啶不同镇静深度下的记忆加工分离程序分析,探讨右美托咪啶消除外显记忆或内隐记忆的镇静深度。方法拟行下肢手术的患者60例,采用随机数字表法分为3组,所有患者均在Narcotrend意识深度监测下靶控输注右美托咪啶镇静,控制术中麻醉意识深度指数(NI)A组65~70,B组55~60,C组45~50。采用心理学界广泛应用的加工分离程序(PDP)结合词干补笔法,通过制定学习表及测试表录音并进行测试,计算外显记忆和内隐记忆成绩,与0进行统计学分析,差异无统计学意义为记忆消失。结果 A组外显记忆和内隐记忆成绩与0相比差异有统计学意义(P0.05);B组外显记忆成绩与0相比差异无统计学意义(P0.05),内隐记忆成绩与0相比差异有统计学意义(P0.05);C组外显记忆和内隐记忆成绩与0相比差异无统计学意义(P0.05)。A、B两组内隐记忆成绩差异无统计学意义(P0.05)。结论意识深度指数(NI)介于65~70时,内隐记忆和外显记忆均未消失,NI降至55~60间时,患者外显记忆成绩消失,但内隐记忆仍存在。NI介于45~50之间时,患者内隐记忆和外显记忆均消失。
[Abstract]:Objective to compare the memory processing and separation procedures of dexmetidine at different sedation depths and to explore the sedation depth of dexmetomidine for eliminating explicit or implicit memory. Methods Sixty patients with lower extremity operation were divided into 3 groups by random digital table method. All the patients were injected with dexmetidine sedation under the depth monitoring of Narcotrend consciousness, and the anesthesia consciousness depth index (NI) A) was controlled in (NI) A group (65,70,60B group). In this paper, the widely used process separation program (PDP) and the word stem complement method are used to calculate the scores of explicit memory and implicit memory by making the learning table and the test table recording and testing, and then making statistical analysis with 0. The difference was not statistically significant for memory loss. Results the scores of explicit memory and implicit memory in group A were significantly different from those in group 0 (P0.05). There was no significant difference between group B and group B (P0.05), but the score of implicit memory was significantly different from that of group C (P0.05). The scores of explicit memory and implicit memory had no significant difference compared with 0 (P0.05). There was no significant difference in implicit memory between two groups (P0.05). Conclusion when the depth of consciousness index (NI) is between 65 and 70, the implicit memory and explicit memory do not disappear. When the implicit memory and explicit memory decrease to 5560, the explicit memory scores of the patients disappear, but the implicit memory and explicit memory disappear when the implicit memory is still between 4550 and 450.Conclusion when the depth of consciousness index (NI) is between 65 and 70, the implicit memory and explicit memory do not disappear.
【作者单位】：南方医科大学附属小榄医院麻醉科;
【基金】：广东省中山市科技计划项目(No:2014A1FC117)
【分类号】：R614

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