小剂量去氧肾上腺素预防剖宫产患者腰—硬联合麻醉后低血压效果观察

发布时间：2018-09-12 18:25

【摘要】：目的观察小剂量去氧肾上腺素预防剖宫产患者腰—硬联合麻醉后低血压的临床效果。方法将拟行剖宫产术的60例患者随机为A、B组各30例,采用腰—硬联合麻醉后,两组均给予液体同步负荷,A组同时应用去氧肾上腺素。观察两组麻醉前后平均动脉压(MAP)和心率(HR)变化及术中情况,记录不良反应发生情况,并于新生儿出生1、5 min进行Apger评分。结果麻醉前后A组MAP及两组HR变化平稳,P均0.05;B组MAP在麻醉10 min后下降,P0.05。A组低血压发生率低于B组,新生儿出生1 min的Apgar评分高于B组,P均0.05。两组鞘内注药至胎儿娩出时间、手术时间、术中输液量及新生儿出生5 min的Apgar评分比较,P均0.05。结论小剂量去氧肾上腺素可有效预防剖宫产患者腰—硬联合麻醉后低血压的发生,且不良反应较小。
[Abstract]:Objective To observe the clinical effect of low dose of deoxyepinephrine in preventing hypotension after combined spinal-epidural anesthesia in cesarean section patients.Methods 60 patients who were going to undergo cesarean section were randomly divided into group A and group B, 30 patients in each group.After combined spinal-epidural anesthesia, both groups were given fluid load synchronously.Group A was given deoxyepinephrine at the same time. Mean arterial pressure (MAP) and heart rate (HR) changes and intraoperative conditions were recorded, adverse reactions were recorded, and Apger score was performed at 1,5 minutes of neonatal birth. Results Before and after anesthesia, MAP and HR in group A and two groups were stable, P 0.05; MAP in group B decreased 10 minutes after anesthesia, the incidence of hypotension in group P 0.05.A was lower than that in group B, and APgar score was higher at 1 minute of neonatal birth. In group B, the time from intrathecal injection to fetal delivery, operation time, intraoperative transfusion volume and the Apgar score at 5 minutes of neonatal birth were all 0.05. Conclusion Low dose of noradrenaline can effectively prevent hypotension after combined spinal-epidural anesthesia in cesarean section patients with less adverse reactions.
【作者单位】：延安大学附属医院;西安交通大学第一附属医院;
【基金】：陕西省科学技术攻关项目(SF2-14) 延安大学研究生科研基金资助项目(12YJ11)
【分类号】：R614

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