重症肌无力患者围术期麻醉管理的进展
发布时间：2018-10-05 12:34
【摘要】：正重症肌无力(myasthenia gravis,MG)是一种由抗体介导的乙酰胆碱(Ach)受体(AchR)受损和功能性AchR减少的自身免疫性疾病,其临床特征是骨骼肌无力和易疲劳,活动后症状加重,休息或予胆碱酯酶抑制剂治疗后可缓解。鉴于其特殊的病理生理,对MG患者的围术期麻醉管理应谨慎。1 MG的病理生理MG是一种自身免疫性疾病,主要由AchR抗
[Abstract]:Positive myasthenia gravis (myasthenia gravis,MG) is an autoimmune disease with impaired (AchR) of acetylcholine (Ach) receptor and decrease of functional AchR mediated by antibody. Its clinical characteristics are skeletal muscle weakness and fatigue, and the symptoms after exercise are aggravated. Rest or treatment with cholinesterase inhibitors may relieve the disease. In view of its special pathophysiology, perioperative anesthesia management of MG patients should be careful. 1. 1 MG pathophysiological MG is an autoimmune disease, which is mainly resistant by AchR.
【作者单位】： 皖南医学院弋矶山医院麻醉与重症医学科;
【基金】：安徽省卫生厅医学科研项目资助(2010C066)
【分类号】：R614
[Abstract]:Positive myasthenia gravis (myasthenia gravis,MG) is an autoimmune disease with impaired (AchR) of acetylcholine (Ach) receptor and decrease of functional AchR mediated by antibody. Its clinical characteristics are skeletal muscle weakness and fatigue, and the symptoms after exercise are aggravated. Rest or treatment with cholinesterase inhibitors may relieve the disease. In view of its special pathophysiology, perioperative anesthesia management of MG patients should be careful. 1. 1 MG pathophysiological MG is an autoimmune disease, which is mainly resistant by AchR.
【作者单位】： 皖南医学院弋矶山医院麻醉与重症医学科;
【基金】：安徽省卫生厅医学科研项目资助(2010C066)
【分类号】：R614
【参考文献】
相关期刊论文 前2条
1 吕宝胜;王卓强;王卫;解恩宇;房芳;张晨;;七氟烷或丙泊酚复合瑞芬太尼麻醉在重症肌无力患者胸腺切除术中的应用[J];解放军医学杂志;2013年07期
2 鲁卫华;金孝\，
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