不同人种和宗教背景手术患者痛阈和帕瑞昔布钠镇痛治疗效果的比较
发布时间：2018-10-26 14:21
【摘要】：目的探讨不同人种和宗教背景的患者痛阈和镇痛治疗效果的差异。方法选取择期在静吸复合全麻下行腹腔镜阑尾炎切除术的18至38岁男性患者48例,采用随机单位组3×2析因设计:将每例入选对象视为1个单位,对每个单位设置2个影响因素,即所在人种因素(3水平:欧罗巴人种、尼格罗人种、蒙古人种)和宗教背景因素(2水平:信仰宗教、不信仰宗教)的所有组合(共6组,n=8)。所有试验对象实施相同的麻醉、手术以及帕瑞昔布钠术后镇痛。在进行镇痛治疗前1 h和镇痛治疗后1 h,分别测量其温度痛阈和电痛阈。结果镇痛治疗前后,欧罗巴人种较尼格罗人种和蒙古人种痛阈高;有宗教信仰与无宗教信仰受试者的温度疼痛感知阈和电疼痛感知阈差异均无统计学意义(镇痛治疗前:F=251.119,P=0.130,F=275.861,P=0.059;镇痛治疗后:F=308.531,P=0.086,F=180.062,P=0.078);人种和宗教因素对温度疼痛感知阈和电疼痛感知阈也不具有交互作用(镇痛治疗前:F=13.553,P=0.091,F=22.001,P=0.089;镇痛治疗后:F=4.624,P=0.089,F=15.935,P=0.094)。结论不同人种的痛阈有一定差异,欧罗巴人种的痛阈最高,尼格罗人种次之,蒙古人种的痛阈最低。有无宗教信仰不能明显影响个体的痛阈。
[Abstract]:Objective to explore the difference of pain threshold and analgesic effect in patients with different ethnic and religious backgrounds. Methods 48 male patients between 18 and 38 years of age undergoing laparoscopic appendicitis resection under general anesthesia were selected. The 3 脳 2 factorial design of random unit group was used: each patient was treated as one unit and 2 influencing factors were set up for each unit. That is, all the combinations of human race factors (level 3: Europa, Negroy, Mongol) and religious background (level 2: religious, non-religious) (6 groups, nun8). All subjects were given the same anesthesia, surgery, and postoperative analgesia with paracyclob sodium. The temperature pain threshold and electric pain threshold were measured 1 hour before analgesia treatment and 1 hour after analgesia treatment. Results before and after analgesia treatment, the pain threshold of Europa was higher than that of Negroes and Mongolians. There was no significant difference in temperature pain perception threshold and electrical pain perception threshold between religious and non-religious subjects. After analgesia treatment, FU 308.531 PnP 0.086 FU 180.062 P0.078) and ethnic and religious factors had no interactive effect on temperature pain perception threshold and electric pain perception threshold (before analgesia treatment: FG13.553 P0. 091 FU 22. 001P0.089), and there was no interaction between ethnic and religious factors on temperature pain perception threshold and electrical pain perception threshold (P 0. 089). After analgesic treatment: FG 4.624m, P = 0.089, F = 15.935, P = 0.094). Conclusion there are some differences in pain threshold among different ethnic groups, the pain threshold of Europa is the highest, that of Negroes is the second, and that of Mongolian is the lowest. There is no religious belief can not significantly affect the pain threshold of the individual.
【作者单位】： 南方医科大学附属南方医院麻醉科;中国人民解放军第452医院麻醉科;天津市胸科医院麻醉科;
【基金】：中国博士后科学基金(2013M530880)~~
【分类号】：R614.2
[Abstract]:Objective to explore the difference of pain threshold and analgesic effect in patients with different ethnic and religious backgrounds. Methods 48 male patients between 18 and 38 years of age undergoing laparoscopic appendicitis resection under general anesthesia were selected. The 3 脳 2 factorial design of random unit group was used: each patient was treated as one unit and 2 influencing factors were set up for each unit. That is, all the combinations of human race factors (level 3: Europa, Negroy, Mongol) and religious background (level 2: religious, non-religious) (6 groups, nun8). All subjects were given the same anesthesia, surgery, and postoperative analgesia with paracyclob sodium. The temperature pain threshold and electric pain threshold were measured 1 hour before analgesia treatment and 1 hour after analgesia treatment. Results before and after analgesia treatment, the pain threshold of Europa was higher than that of Negroes and Mongolians. There was no significant difference in temperature pain perception threshold and electrical pain perception threshold between religious and non-religious subjects. After analgesia treatment, FU 308.531 PnP 0.086 FU 180.062 P0.078) and ethnic and religious factors had no interactive effect on temperature pain perception threshold and electric pain perception threshold (before analgesia treatment: FG13.553 P0. 091 FU 22. 001P0.089), and there was no interaction between ethnic and religious factors on temperature pain perception threshold and electrical pain perception threshold (P 0. 089). After analgesic treatment: FG 4.624m, P = 0.089, F = 15.935, P = 0.094). Conclusion there are some differences in pain threshold among different ethnic groups, the pain threshold of Europa is the highest, that of Negroes is the second, and that of Mongolian is the lowest. There is no religious belief can not significantly affect the pain threshold of the individual.
【作者单位】： 南方医科大学附属南方医院麻醉科;中国人民解放军第452医院麻醉科;天津市胸科医院麻醉科;
【基金】：中国博士后科学基金(2013M530880)~~
【分类号】：R614.2
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