依托咪酯乳剂与丙泊酚在老年人无痛诊断性刮宫术中应用效果的比较

发布时间：2018-11-27 16:11

【摘要】：目的比较依托咪酯乳剂与丙泊酚用于老年人无痛诊断性刮宫术的效果。方法拟行诊断性刮宫术的老年患者60例,随机分为A组和B组,每组30例。手术开始前A组静脉注射丙泊酚1.5 mg/kg,B组静脉注射依托咪酯乳剂0.25 mg/kg,记录手术时间、麻醉苏醒时间、恢复行走时间,观察麻醉用药前(T0)、注药后1 min(T1)、5 min(T2)、患者清醒时(T3)的MAP和HR的变化,记录注射痛、术中体动、低血压、心动过缓、低氧血症及术后恶心、呕吐的发生率。结果 A组T1时点MAP低于其他时点(P0.05),T2时点MAP低于T0、T3时点(P0.05)。A组T1、T2时点MAP低于B组(P0.05),B组注射痛、低血压和低氧血症发生率低于A组(P0.05)。结论与丙泊酚相比,依托咪酯乳剂用于老年人无痛诊断性刮宫术,对循环和呼吸的影响小,注射痛发生率低。
[Abstract]:Objective to compare the efficacy of etomidate emulsion and propofol in painless and diagnostic curettage in the elderly. Methods 60 elderly patients undergoing diagnostic curettage were randomly divided into group A and group B with 30 cases in each group. Before the operation, group A received propofol 1.5 mg/kg,B intravenous etomidate emulsion 0.25 mg/kg, to record the operation time, anesthesia recovery time, recovery walking time, observe before anesthesia (T0). 1 min (T1), 5 min (T2), the changes of MAP and HR during waking (T3), the incidence of injection pain, intraoperative body movement, hypotension, bradycardia, hypoxemia and postoperative nausea and vomiting were recorded. Results in group A, MAP at T1 was lower than that at other time points (P0.05), MAP at T2 was lower than that at T0 / T3 (P0.05) MAP at T1 and T2 in). A group was lower than that in group B (P0.05), MAP in group), B was lower than that in group B (P0.05). The incidence of hypotension and hypoxemia was lower than that in group A (P0.05). Conclusion compared with propofol, etomidate emulsion has less effect on circulation and respiration and lower incidence of injection pain in elderly patients with painless and diagnostic curettage.
【作者单位】：暨南大学第二临床医学院广东省深圳市人民医院麻醉科;
【分类号】：R614

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