丙泊酚、芬太尼复合小剂量咪唑安定静脉麻醉在妇产科门诊手术中的应用效果

发布时间：2018-12-11 23:35

【摘要】：目的分析丙泊酚注射液、芬太尼与小剂量咪唑安定三种麻醉药物在妇产科门诊手术中的麻醉效果。方法选取我院妇产科门诊的60例患者作为研究对象,将其随机分为PF组和PFM组,每组30例。PF组使用丙泊酚复合芬太尼进行麻醉;PFM组在PF组的基础上加用小剂量咪唑安定进行麻醉。监测记录两组患者不同时间段的平均动脉压(MAP)、心率(HR)、呼吸(RR)以及脉搏血氧饱和度(Sp O_2),并观察两组患者麻醉的药物起效时间、手术时间、苏醒时间及丙泊酚用量情况和不良反应发生情况。结果两组患者麻醉后的MAP、HR、RR及Sp O_2的最低值明显低于麻醉前(P0.05);手术结束后PF组RR、Sp O_2值明显低于PFM组(P0.05);两组患者的麻醉起效时间、苏醒时间,组间比较无明显差异(P0.05);PFM组的丙泊酚用量明显低于PF组(P0.05);两组患者的术中体动、术后嗜睡、乏力、头晕、恶心、呕吐等不良反应发生率比较,无明显差异(P0.05)。结论丙泊酚+芬太尼+小剂量咪唑安定用于妇产科门诊的麻醉手术相比丙泊酚+芬太尼麻醉效果更佳,风险更低。
[Abstract]:Objective to analyze the anesthetic effect of propofol injection, fentanyl and low dose midazolam in outpatient department of gynecology and obstetrics. Methods Sixty patients in gynecology and obstetrics clinic were randomly divided into PF group and PFM group with 30 cases in each group. PF group was anesthetized with propofol and fentanyl. PFM group was anesthetized with midazolam on the basis of PF group. Mean arterial pressure (MAP), heart rate (HR), respiration (RR) (RR) and Sp oxygen saturation (Sp O _ 2) were recorded in two groups at different time periods. The onset time of anaesthesia and the time of operation were observed. Recovery time, propofol dosage and adverse reactions. Results the minimum values of MAP,HR,RR and Sp O _ 2 after anesthesia in both groups were significantly lower than those before anesthesia (P0.05), RR,Sp _ O _ 2 in PF group after operation was significantly lower than that in PFM group (P0.05). There was no significant difference between the two groups in the onset time and recovery time of anesthesia (P0.05). The dosage of propofol in); PFM group was significantly lower than that in PF group (P0.05). There was no significant difference between the two groups in the incidence of adverse reactions such as body movement postoperative lethargy fatigue dizziness nausea and vomiting (P0.05). Conclusion propofol fentanyl low dose midazolam is more effective and less risky than propofol fentanyl anesthesia in gynecology and obstetrics outpatient.
【作者单位】：陕西省渭南市第一医院妇产科;陕西省渭南市第一医院消化呼吸内科;
【分类号】：R614

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