七氟醚联合异丙酚用于胸科手术单肺通气患者麻醉中的效果观察

发布时间：2019-02-23 17:13

【摘要】：目的探讨七氟醚联合异丙酚用于胸外科手术单肺通气患者麻醉中的临床效果。方法回顾性选取2014年6—12月吉林市中心医院收治的胸外科手术单肺通气患者70例,按随机数字表法将其分为观察组与对照组,各35例。观察组患者给予七氟醚联合异丙酚麻醉,对照组患者仅给予七氟醚吸入麻醉,比较两组患者麻醉前(T0)、手术切皮前5 min(T1)、手术切皮后5 min(T2)、单肺通气期(T3)、手术结束前10 min(T4)的动脉血氧饱和度(Sa O2)、动脉血氧分压(Pa O2)、动脉二氧化碳分压(Pa CO2)、平均动脉压(MAP)、心率(HR)变化情况以及自主呼吸恢复时间、睁眼时间、拔管时间。结果 T1、T4时点,观察组患者MAP及HR均明显低于对照组,差异均有统计学意义(均P0.05);T3时点,观察组患者的Sa O2明显高于对照组,差异有统计学意义(P0.05);T1、T2、T3、T4时点,观察组患者的Pa O2明显高于对照组,差异有统计学意义(P0.05);观察组患者自主呼吸恢复时间、睁眼时间、拔管时间均明显短于对照组,差异均有统计学意义(均P0.05)。结论七氟醚联合异丙酚在胸外科手术单肺通气患者麻醉中的应用效果明显,可有效降低麻醉风险,术后患者苏醒快,有利于外科手术的顺利进行。
[Abstract]:Objective to investigate the clinical effect of sevoflurane combined with propofol in single-lung ventilation patients undergoing thoracic surgery. Methods A total of 70 patients with single lung ventilation treated in Jilin City Central Hospital from June to December 2014 were selected retrospectively and divided into observation group (35 cases) and control group (35 cases) according to the method of random digital table. The patients in the observation group were given sevoflurane combined with propofol anesthesia, while the patients in the control group were only given sevoflurane inhalation anesthesia. The patients in the two groups were compared before anesthesia (T0), 5 min before operation (T1) and 5 min after incision (T2). One-lung ventilation (T3), arterial oxygen saturation (Sa O 2), partial arterial oxygen pressure (Pa O 2), arterial carbon dioxide partial pressure (Pa CO2), mean arterial pressure (MAP),) 10 min before the end of surgery (T4) The changes of heart rate (HR), the time of spontaneous respiratory recovery, the time of eye opening and the time of extubation. Results the MAP and HR in the observation group were significantly lower than those in the control group (P0.05), the Sa O2 in the observation group was significantly higher than that in the control group at T3 time point (P0.05). The Pa O 2 of the patients in the observation group was significantly higher than that in the control group at the time point of T 1 and T 2, and the difference was statistically significant (P 0.05). The time of spontaneous respiration recovery, eye opening and extubation in the observation group were significantly shorter than those in the control group (P0.05). Conclusion sevoflurane combined with propofol is effective in single lung ventilation in thoracic surgery and can effectively reduce the risk of anesthesia.
【作者单位】：吉林市中心医院;
【分类号】：R614

【参考文献】