右旋美托咪定在纤维支气管镜引导气管插管全麻甲状腺手术的应用

发布时间：2019-03-24 18:46

【摘要】：目的:研究右旋美托咪定(dexmedetomidine,Dex)对全麻甲状腺手术患者接受纤维支气管镜(fiberoptic bronchoscope,FOB)引导经口气管插管的影响。方法:拟行经口气管插管全麻甲状腺手术患者80例,美国麻醉医师协会(American Society of Anesthesiology,ASA)I~Ⅲ级,年龄29~71岁,随机分为两组(n=40):Dex组(D组)及安慰剂组(P组)。诱导前两组患者分别以Dex(1μg·kg-1,4μg·m L-1)和等量生理盐水泵入15 min,随后常规麻醉诱导,以FOB行经口气管插管,记录入室后5 min(基础值)、麻醉诱导前、气管插管前、气管插管即刻及气管插管后1,2,3,5,10 min的血压、心率和脑电双频指数(bispectral idex,BIS)。观察患者气管插管的血流动力学变化及相关并发症。结果:与P组患者相比,麻醉诱导和气管插管期间,D组患者血流动力学平稳(P0.05),并发症发生率低(但P0.05)。结论:麻醉诱导前输注Dex,可以减轻FOB引导气管插管血液动力学反应并减少其相关并发症。
[Abstract]:Aim: to study the effect of dexmetometomidine (dexmedetomidine,Dex) on transoral intubation guided by fiberoptic bronchoscopy (fiberoptic bronchoscope,FOB) in patients undergoing thyroid surgery under general anesthesia. Methods: eighty patients undergoing general anesthesia under general anesthesia were randomly divided into two groups (n = 40): Dex, group D) and placebo group (group P), aged 29 / 71 years. (American Society of Anesthesiology,ASA, American Association of anesthesiologists, was grade I ~ 鈪，

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