丁丙诺啡复合咪唑安定用于硬膜外麻醉的临床观察
发布时间：2019-05-15 05:11
【摘要】：目的观察静脉注射丁丙诺啡-咪唑安定辅助硬膜外麻醉时的镇静、消除内脏牵拉反应效果和对呼吸、循环的影响。方法硬膜外麻醉下行下腹部手术患者40例,随机分为B组(丁丙诺啡0.15mg+咪唑安定4mg为1U)和F组(芬太尼0.1mg+咪唑安定4mg为1U),每组20例。手术开始前5min静脉缓慢注射辅助药物3/4-1U。观察并记录用药时和用药后5、15、30min平均动脉压、心率、脉搏血氧饱和度和呼吸频率,以及患者镇静程度和术中发生的牵拉反应。结果 B组的镇静、消除内脏牵拉反应的作用明显强于F组(P0.05);两组对循环及呼吸均无明显影响(P0.05)。结论丁丙诺啡-咪唑安定能安全地辅助于硬膜外麻醉,能有效的增强镇静和消除内脏牵拉反应,对呼吸和循环无明显影响。
[Abstract]:Objective to observe the sedation of buprenorphine midazolam assisted epidural anesthesia and to eliminate the effect of visceral traction and respiration and circulation. Methods 40 patients undergoing lower abdominal surgery under epidural anesthesia were randomly divided into group B (buprenorphine 0.15mg midazolam 4mg 1U) and group F (fentanyl 0.1mg midazolam 4mg 1U) with 20 patients in each group. Before the beginning of the operation, 5min was slowly injected intravenously with 3 脳 4 脳 1 U 路L ~ (- 1) g 路L ~ (- 1). The mean arterial pressure, heart rate, pulse oxygen saturation and respiratory rate, sedation degree and intraoperative traction reaction were observed and recorded at 15, 15 and 30 min after treatment. Results the sedation and elimination of visceral traction reaction in group B were significantly stronger than those in group F (P 0.05), but there was no significant effect on circulation and respiration in group B (P 0.05). Conclusion buprenorphine midazolam can safely assist epidural anesthesia, can effectively enhance sedation and eliminate visceral traction reaction, and has no significant effect on respiration and circulation.
【作者单位】： 福建省福鼎市医院麻醉科;
【分类号】：R614.42
，
本文编号：2477334
[Abstract]:Objective to observe the sedation of buprenorphine midazolam assisted epidural anesthesia and to eliminate the effect of visceral traction and respiration and circulation. Methods 40 patients undergoing lower abdominal surgery under epidural anesthesia were randomly divided into group B (buprenorphine 0.15mg midazolam 4mg 1U) and group F (fentanyl 0.1mg midazolam 4mg 1U) with 20 patients in each group. Before the beginning of the operation, 5min was slowly injected intravenously with 3 脳 4 脳 1 U 路L ~ (- 1) g 路L ~ (- 1). The mean arterial pressure, heart rate, pulse oxygen saturation and respiratory rate, sedation degree and intraoperative traction reaction were observed and recorded at 15, 15 and 30 min after treatment. Results the sedation and elimination of visceral traction reaction in group B were significantly stronger than those in group F (P 0.05), but there was no significant effect on circulation and respiration in group B (P 0.05). Conclusion buprenorphine midazolam can safely assist epidural anesthesia, can effectively enhance sedation and eliminate visceral traction reaction, and has no significant effect on respiration and circulation.
【作者单位】： 福建省福鼎市医院麻醉科;
【分类号】：R614.42
，
本文编号：2477334
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