右美托咪啶联合瑞芬太尼在全身麻醉中的研究分析

发布时间：2019-06-26 11:42

【摘要】：目的:分析右美托咪啶联合瑞芬太尼在全身麻醉中的临床应用效果。方法:收集需进行全身麻醉手术的94例患者为研究对象,将其随机分为观察组与对照组,观察组给予右美托咪啶联合瑞芬太尼麻醉,对照组给予瑞芬太尼联合丙泊酚进行麻醉,对比分析两组患者麻醉诱导前、麻醉2 min后、拔管时、拔管后20 min其平均动脉压(MAP)、心率(HR)及不良反应发生情况。结果:与麻醉诱导前比较,两组患者麻醉2 min后、拔管时、拔管后20 min等时间点MAP、HR差异均有统计学意义(P0.05);且拔管时及拔管后20 min两组患者MAP、HR差异有统计学意义(P0.05)。观察组不良反应发生率为8.51%,低于对照组的25.53%,差异有统计学意义(P0.05)。结论:右美托咪啶联合瑞芬太尼在全身麻醉中的临床应用效果显著,建议在临床上推广。
[Abstract]:Objective: to analyze the clinical effect of dexmetomidine combined with remifentanil in general anesthesia. Methods: 94 patients undergoing general anesthesia were randomly divided into observation group and control group. The observation group was anesthetized with right metomidate combined with remifentanil, and the control group was anesthetized with remifentanil combined with propofol. Before anesthesia induction, after 2 min anesthesia, 20 min after extubation, the mean arterial pressure (MAP), heart rate (HR) and adverse reactions were compared between the two groups. Results: compared with those before anesthesia induction, there were significant differences in MAP,HR between the two groups at the time of 2 min, extubation and 20 min after extubation (P 0.05), and there was significant difference in MAP,HR between the two groups at extubation and 20 min after extubation (P 0.05). The incidence of adverse reactions in the observation group was 8.51%, which was lower than that in the control group (25.53%), the difference was statistically significant (P 0.05). Conclusion: the clinical application of dexmetomidine combined with remifentanil in general anesthesia is effective, and it is suggested that it should be popularized in clinic.
【作者单位】： 中国人民解放军第159中心医院麻醉科;
【分类号】：R614.2
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本文编号：2506154