不同剂量瑞芬太尼对小儿七氟烷麻醉自主呼吸的影响比较分析

发布时间：2019-07-21 16:28

【摘要】：目的分析临床手术中瑞芬太尼剂量的多少对小儿七氟烷麻醉自主呼吸的影响。方法选取2013年5月~2015年5月我院进行外科手术的患儿90例作为研究对象,将其随机分为A、B、C组,各30例。其中A组术中使用瑞芬太尼的剂量为0.03μg/(kg·min),B组为0.06μg/(kg·min),C组为0.09μg/(kg·min),三组对比差异无统计学意义(P0.05),比较喉罩置入并实施持续推注后患儿生命体征的差异。结果三组患儿在不同时段的HR值并无显著差异;T1、T2时RR值各组间对比,差异均无统计学意义(P0.05),T3、T4、T5时,C组均低于A组和B组,A组和B组对比,差异无统计学意义(P0.05)。结论 0.09μg/(kg·min)剂量的瑞芬太尼在术中实施持续推注会抑制患儿的自主呼吸,而0.03~0.06μg/(kg·min)的瑞芬太尼能减轻小儿七氟烷麻醉自主呼吸的抑制作用,在一定程度上保留了患儿的自主呼吸。
[Abstract]:Objective to analyze the effect of remifentanil dose on spontaneous respiration under sevoflurane anesthesia in children. Methods from May 2013 to May 2015, 90 children undergoing surgery in our hospital were randomly divided into A group (n = 30) and group C (n = 30). The dose of remifentanil in group A was 0.03 渭 g / (0.06 渭 g / in kg 路min), B group) and 0.09 渭 g / (0.09 渭 g /) in kg 路min), C group (P 0.05). There was no significant difference in vital signs after laryngeal mask implantation and continuous injection. Results there was no significant difference in HR values among the three groups at different time points, but there was no significant difference in RR values among the three groups at T1 and T2. at T3, T4 and T5, the HR values in group C were lower than those in group A and group B, and there was no significant difference between group A and group B (P 0.05). Conclusion 0.09 渭 g / (kg 路min) remifentanil can inhibit the spontaneous respiration of children during operation, while remifentanil 0.03 ~ 0.06 渭 g / (kg 路min) can alleviate the inhibitory effect of sevoflurane anesthesia on spontaneous respiration in children, and retain the spontaneous respiration to a certain extent.
【作者单位】：河南省驻马店市中心医院;
【分类号】：R726.1

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