非阿片药物复合推管内麻醉在大肠癌手术中使用的可行性研究
发布时间:2019-08-06 12:51
【摘要】:目的分析非阿片药物复合推管内麻醉在大肠癌手术中使用的可能性。方法将75例各类(腔镜和开腹)大肠癌手术的患者分为阿片药物麻醉(A组)、阿片药物复合椎管内麻醉(H组)、非阿片药物复合椎管内麻醉(F组)3组。记录不同阶段的熵指数、心率(HR)、平均动脉压(MAP)、苏醒时间、拔管时间、患者术前和术后各时间点疼痛的VAS评分、术后肛门排气时间;术后住院时间;并采用ELISA测试血清干扰素-γ(INF-γ)及白细胞介素(IL)-6、IL-10的水平。结果 3组患者麻醉时的熵指数、HR及MAP比较差异无统计学意义(P0.05);F组患者的苏醒时间、拔管时间与A、H组比较,差异有统计学意义(P0.05);H、F组患者的VAS评分显著低于A组(P0.05),但H、F组比较差异无统计学意义(P0.05);3组患者术后肛门排气时间与住院时间比较差异无统计学意义(P0.05);手术3d后,H、F组患者的IFN-γ水平高于A组(P0.05),但H、F组比较差异无统计学意义(P0.05);手术1d后,A组患者的IL-6水平高于H、F组(P0.05),但H、F组比较差异无统计学意义(P0.05);手术完毕时,A组患者的IL-10水平明显高于H、F组(P0.05),但H、F组比较差异无统计学意义(P0.05)。结论基于样本分析结果,非阿片药物复合椎管内麻醉对大肠癌手术患者可能有更好的保护作用,对患者的术后恢复有更好的促进作用。
[Abstract]:Objective to analyze the possibility of non-opioid combined tubule anesthesia in colorectal cancer surgery. Methods 75 patients undergoing colorectal cancer surgery were divided into three groups: opioid anesthesia (group A), opioid combined with intraspinal anesthesia (group H) and non-opioid combined with intraspinal anesthesia (group F). Entropy index, heart rate (HR), mean arterial pressure (MAP), recovery time, extubation time, VAS score of pain before and after operation, postoperative anal exhaust time, postoperative hospitalization time, serum interferon-gamma (INF- 纬) and IL-6, IL 鈮,
本文编号:2523557
[Abstract]:Objective to analyze the possibility of non-opioid combined tubule anesthesia in colorectal cancer surgery. Methods 75 patients undergoing colorectal cancer surgery were divided into three groups: opioid anesthesia (group A), opioid combined with intraspinal anesthesia (group H) and non-opioid combined with intraspinal anesthesia (group F). Entropy index, heart rate (HR), mean arterial pressure (MAP), recovery time, extubation time, VAS score of pain before and after operation, postoperative anal exhaust time, postoperative hospitalization time, serum interferon-gamma (INF- 纬) and IL-6, IL 鈮,
本文编号:2523557
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