原发性睾丸恶性淋巴瘤12例诊治分析

发布时间：2018-02-05 21:02

本文关键词： 睾丸肿瘤淋巴瘤诊断治疗预后　出处：《中国全科医学》2017年36期 　论文类型：期刊论文

【摘要】：目的分析原发性睾丸恶性淋巴瘤12例(PTML)患者的诊治资料,提高临床医生对该病的认识及诊治水平。方法回顾性分析1995年1月—2016年1月承德医学院附属医院泌尿外科收治的12例PTML患者的临床资料,包括PTML患者的一般资料、影像学检查结果、病理检查结果、治疗情况、随访情况。结果 12例PTML患者年龄24~78岁,其中60岁者(9/12)居多;病程1~14个月;肿瘤发生在右侧睾丸者(6/12)居多;主要症状为患侧睾丸肿大、伴有阴囊坠胀。12例患者均行B超检查,仅显示睾丸内低回声或实性肿物,提示睾丸占位。9例患者行睾丸CT检查,显示患侧睾丸增大,病灶边缘清晰或不清晰,密度相对均匀。术后病理检查诊断为弥漫性大B细胞淋巴瘤。12例PTML患者均行根治性睾丸切除术,其中4例患者术后联合放疗,5例患者术后联合放、化疗。随访12~120个月,死亡8例,其中3例死于肺转移,3例死于全身转移,1例死于脑转移,1例死于心脑血管疾病;其余4例在26~120个月存活良好。结论 PTML临床较少见,60岁以上体格检查有睾丸肿块者应首先考虑恶性淋巴瘤的可能,手术联合放、化疗可提高临床疗效。
[Abstract]:Objective to analyze the diagnosis and treatment of primary testicular malignant lymphoma in 12 patients with PTMLs. Methods the clinical data of 12 patients with PTML in urology department of Chengde Medical College from January 1995 to January 2016 were analyzed retrospectively. . Including general data, imaging findings, pathological findings, treatment, and follow-up of PTML patients. Results 12 patients with PTML were 24 to 78 years old. Most of them were 60 years old (9 / 12); The course of disease was 1 ~ 14 months. Most tumors occurred in the right testis (6 / 12). The main symptoms were testicular enlargement and scrotal distention. All the 12 cases were examined by B-mode ultrasound, only hypoechoic or solid mass in the testis was shown, indicating that 9 cases of testicular mass were examined by testicular CT. All the 12 patients with PTML underwent radical orchiectomy. Four patients were followed up for 12 ~ 120 months, 8 died, 3 died of lung metastasis, 3 died of systemic metastasis and 1 died of brain metastasis. 1 case died of cardiovascular and cerebrovascular diseases. The other 4 cases survived well for 26 ~ 120 months. Conclusion the possibility of malignant lymphoma should be considered first in patients with testicular mass over 60 years of age in PTML. Chemotherapy can improve the clinical efficacy.
【作者单位】：河北省平泉市医院普外科;承德医学院附属医院泌尿外科;
【分类号】：R737.21

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