恙虫病患者发生急性肾损伤的临床研究

发布时间：2018-03-11 03:26

本文选题：急性肾损伤　切入点：恙虫病　出处：《广东医学》2017年02期 　论文类型：期刊论文

【摘要】：目的探讨急性肾损伤(AKI)在恙虫病,尤其在恙虫病重症病例中的发生情况及危害,并探索预测AKI发生的因素。方法收集307例恙虫病的临床资料,将所有病例分为AKI组和非AKI组,分析两组病例发生多器官功能障碍综合征(MODS)、死亡、肝损害的情况,以及两组年龄、住院费用、热程的差异及血小板、白细胞、降钙素原(PCT)检测值的差异。结果 307例病例发生AKI 33例(10.8%);MODS 14例,其中10例(71.4%)分布在AKI组;死亡病例5例均分布在AKI组;AKI组患者平均年龄、平均住院费用、MODS发生比例、肝损害发生比例、血小板减少者比例、白细胞增多者比例均高于非AKI组,差异有统计学意义(P0.05)。两组热程差异无统计意义(P0.05)。结论恙虫病患者发生AKI比例低,程度轻,但AKI可能促进恙虫病重症化及死亡;年龄,PCT、白细胞、血小板检测可能有助于预测AKI的发生。
[Abstract]:Objective to investigate the incidence and harm of acute renal injury (ABI) in patients with tsutsugamushi disease, especially in severe cases of tsutsugamushi disease, and to explore the prognostic factors of AKI. Methods Clinical data of 307 patients with tsutsugamushi disease were collected and divided into AKI group and non-#en2# group. To analyze the incidence of multiple organ dysfunction syndrome (MODS), death, liver damage, age, hospitalization cost, fever course, platelets, white blood cells in the two groups. Results AKI was found in 33 cases (10.8%) in 14 patients with mods (10 cases) in AKI group, and 5 cases in AKI group. The incidence of liver damage, thrombocytopenia and leukopenia were significantly higher in patients with liver injury than in non-patients with AKI, and the difference was statistically significant (P 0.05). Conclusion the incidence of AKI in patients with tsutsugamushi disease is low and the degree is slight. But AKI may promote the severity and death of tsutsugamushi disease, and the detection of age, leukocytes and platelets may help to predict the occurrence of AKI.
【作者单位】：广东医科大学附属医院感染内科中心;广东医科大学附属医院急诊科;广东医科大学附属医院儿童医学中心;广东医科大学附属医院肾脏病研究所;广东医科大学附属医院心血管内科中心;广东医科大学公共卫生学院劳动卫生与环境卫生学教研室;
【分类号】：R513.2;R692.5

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