WONCA研究论文摘要汇编——前列腺癌患者是否采取积极治疗对预期寿命的影响研究

发布时间：2018-03-12 15:19

本文选题：WONCA　切入点：前列腺癌患者　出处：《中国全科医学》2016年22期 　论文类型：期刊论文

【摘要】：目的目前积极治疗(手术或放射治疗)在局限性前列腺癌(LPC)患者中的临床获益尚不明确,故LPC的过度医疗筛查仍然是一项重要的公共卫生问题,本研究旨在探讨是否采取积极治疗对LPC患者预期寿命的影响。方法选取年龄≤75岁的近期确诊LPC患者260例,其中黑色人种132例,白色人种128例。采用自填式问卷调查不同治疗方案患者的预期寿命,并采用多因素分析探讨患者预期寿命的影响因素。结果在未采取积极治疗的患者中,33%预期寿命5年,41%预期寿命5~10年,21%预期寿命11~20年,5%预期寿命20年;在采取积极治疗的患者中,3%预期寿命5年,9%预期寿命5~10年,33%预期寿命11~20年,55%预期寿命20年。不同治疗方案选择情况、健康观念、已知癌症严重程度患者的预期寿命间有差异,而不同种族、实际肿瘤风险患者的预期寿命间无差异。对其他因素进行调整后,选择手术或放射治疗患者的预期寿命长于未选择积极治疗或选择积极监测治疗的患者。结论大部分LPC患者低估了自身不采取积极治疗后的预期寿命,而高估了选择手术或放射治疗等积极治疗后的预期寿命。不合理的预期可能会影响到患者选择正确治疗方案的能力,导致LPC过度医疗的发生,临床医生应帮助参与个人治疗决策的患者做出合理预期和治疗选择。
[Abstract]:The purpose of the active treatment (surgery or radiotherapy) in localized prostate cancer (LPC) clinical benefit in patients with excessive medical screening is not clear, so LPC is still an important public health problem, this study aims to investigate whether to take active treatment effect on patients with LPC. Methods the life expectancy of older than the 75 year old recently diagnosed LPC patients 260 cases, including 132 cases of black and white in 128 cases. Using a self-administered questionnaire of life expectancy of different treatment of patients, and to analyze the impact on life expectancy factors. By using multi factor results in not taking positive patients, 33% life expectancy of 5 years. 41% 5~10 21% years of life expectancy, life expectancy of 11~20 5% years, life expectancy of 20 years; in the actively treated patients, 3% life expectancy of 5 years, 9% years life expectancy of 5~10 33%, 11~20 55% years of life expectancy, the life expectancy of 20 years. The same treatment options, concepts of health, life expectancy of known cancer severity in patients with the difference between the different races, but, no difference in life expectancy with the actual risk of cancer. After adjustment for other factors, choice of surgery or radiation therapy in patients with life expectancy than the non active treatment or choose active surveillance treatment conclusion the majority of patients. LPC patients underestimate their own do not take life expectancy after active treatment, and overestimated the life expectancy of surgical operation or radiotherapy after active treatment. Unreasonable expectations may affect the patients ability to choose the right treatment plan, LPC lead to excessive medical treatment, clinicians should help individuals involved in treatment decisions the patients choose to make reasonable expectations and treatment.

【分类号】：R737.25

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