0.9%盐水既不正常也不生理（英文）

发布时间：2018-03-13 02:35

本文选题：.%氯化钠溶液(盐水)　切入点：高氯血症　出处：《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2016年03期 　论文类型：期刊论文

【摘要】：本文旨在客观评价0.9%氯化钠溶液(盐水)的生物化学和病理生理学特性,并深入探讨静脉输注该盐水对机体酸碱平衡和肾脏血流动力学的影响。研究表明多数临床医生对电解质平衡的认识有限,对静脉输注盐水所引起的血浆电解质变化认识不足。而错误地应用盐水会增加患者的患病率和死亡率。健康成人大剂量(2L)输注盐水会导致高氯血症并进而引起代谢性酸中毒、高钾血症和负氮平衡。总之,盐水是一种高度酸化的液体,用于治疗呕吐或上消化道减压引起的低氯性代谢性碱中毒和容量不足较为合适。临床上不加区分地应用盐水对患者特别是对重症患者可能导致不必要的并发症,应注意避免。临床医生对于盐水相关作用和电解质管理的认识亟需增强。
[Abstract]:The objective of this paper is to evaluate the biochemical and pathophysiological properties of 0.9% sodium chloride solution (brine). The effects of intravenous infusion of the saline on the balance of acid and base and renal hemodynamics were also studied. The results showed that most clinicians had limited knowledge of electrolyte balance. There is a lack of understanding of the changes in plasma electrolytes caused by intravenous saltwater infusion. However, the wrong use of salt water increases the morbidity and mortality of patients. The saline infusion of healthy adults can lead to hyperchloremia and, in turn, metabolic acidosis. Hyperkalemia and negative nitrogen balance. In short, brine is a highly acidified liquid, Low chlorine metabolic alkalosis and insufficient volume due to vomiting or upper gastrointestinal decompression are more appropriate. Clinical use of saline without distinction may lead to unnecessary complications in patients, especially in severe cases, Attention should be paid to avoid. Clinicians' understanding of brine-related roles and electrolyte management needs to be enhanced.
【作者单位】： Kidney
【基金】：support of the ISN Sister Renal Center Program
【分类号】：R692

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