老年糖尿病患者并发肾病的危险因素

发布时间：2018-03-18 01:35

本文选题：糖尿病肾病　切入点：空腹血糖　出处：《中国老年学杂志》2017年17期 　论文类型：期刊论文

【摘要】：目的探讨老年糖尿病患者并发肾病的危险因素。方法选择老年糖尿病患者155例作为研究对象。所有患者按照是否患有糖尿病肾病(DN)分为DN组45例和非DN组110例。对DN发病的危险因素[性别、体重指数(BMI)、高血压病史、吸烟、饮酒、晨起空腹血糖(FPG)、糖化血红蛋白(Hb A1c)、血尿酸(UA)、C反应蛋白(CRP)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)和血清总胆固醇(TC)]进行统计学分析。结果单因素分析确定晨起FPG、Hb A1c、血UA、CRP、TG、LDL-C与DN发生有关(P0.05)。进一步对筛选后的变量进行Logistic多因素分析,结果表明晨起FPG、Hb A1c、CRP和LDL-C与患者DN发生相关,其风险系数(OR)分别为1.673、1.772、1.547和1.676(P0.05)。结论晨起FPG、Hb A1c、CRP和LDL-C是DN发病的危险因素,临床上应针对这些因素对相应患者采取预防措施。
[Abstract]:Objective to investigate the risk factors of diabetic nephropathy in elderly patients. Methods 155 elderly patients with diabetes mellitus were divided into DN group (n = 45) and non-DN group (n = 110) according to whether they had diabetic nephropathy or not. Risk factors for DN [gender]. Body mass index (BMI), hypertension history, smoking, drinking, In the morning, fasting blood glucose level (FPG), glycosylated hemoglobin (HbA1cU), serum uric acid (UAA) C-reactive protein (CRP), triglyceride (TGN), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) and serum total cholesterol (TC) were analyzed statistically. From morning to morning, it was determined that HDL-C was related to the occurrence of DNs. The Logistic multivariate analysis was carried out on the selected variables, and the results were as follows: (1) the Logistic multivariate analysis showed that LDL-C was related to the occurrence of DN. The results showed that CRP and LDL-C were correlated with the occurrence of DN in the morning, and their risk coefficients were 1.673 / 1.772n 1.547 and 1.676g / L P0.050.Conclusion FPGG / HbA1cFC-CRP and LDL-C are risk factors of DN, and preventive measures should be taken against these factors in clinic.
【作者单位】：四川省人民医院老年医学科;
【分类号】：R587.2;R692.9

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