斑点追踪技术评价尿毒症与原发性高血压左心室应变

发布时间：2018-03-27 16:25

本文选题：超声心动描记术　切入点：斑点追踪技术　出处：《吉林大学》2014年硕士论文

【摘要】：目的：应用二维斑点追踪技术（STI）比较尿毒症高血压患者与同水平的原发性高血压患者左心室纵向应变。比较心脏的形态，进一步分析左室收缩、舒张功能。在此基础上探讨其对指导治疗和提示预后的临床意义。方法：分别采集30例临床确诊尿毒症患者（尿毒症组）、30例临床确诊的原发性高血压患者（高血压组）与30例正常对照者（对照组）心尖四腔心、三腔心、二腔心的超声动态图像，测量并记录3组常规超声心动图各项心功能指标，应用QLab软件进行分析，测量左心室基底段、中间段、心尖段的应变峰值，记录左心室各节段应变时间变化曲线，并进行比较。应用SPSS17.0软件进行统计学处理，采用t-Test分析，结果以Mean±SD表示，P0.05为有统计学差异。结果： 1.高血压组及尿毒症组的GL、LS2、LS3、 LS4均较正常对照组减低，除LS2外，，高血压组较尿毒症组减低更明显，差异有统计学意义(P0．05)。 2.高血压组及尿毒症组均较正常对照组达峰时间标准差延长，差异有统计学意义（P0.05），但高血压组与尿毒症组两者间无统计学意义（P0.05）。 3.原发性高血压患者较同血压水平的尿毒症患者左室纵向应变峰值减低。结论： 1尿毒症与原发性高血压心肌改变患者左室壁运动均异于正常人；原发性高血压患者的心肌变形能力改变更明显。 2STI技术可以准确的评价尿毒症患者及原发性高血压患者的左室心肌纵向应变。 3STI技术可以间接反映尿毒症及原发性高血压这两种疾病对心肌的不同影响。
[Abstract]:Objective: to compare the longitudinal strain of left ventricle between patients with uremic hypertension and patients with essential hypertension at the same level, to compare the shape of the heart, and to further analyze the left ventricular contraction by using two dimensional dot tracing technique (STI). To explore the clinical significance of diastolic function in guiding treatment and prognosis. Methods: 30 patients with clinically diagnosed uremia (uremia group, 30 patients with essential hypertension) and 30 normal controls (control group) were collected. The cardiac function indexes of three groups of conventional echocardiography were measured and recorded. The peak strain of left ventricular basal segment, middle segment and apical segment were measured by QLab software. The strain time curves of each segment of the left ventricle were recorded and compared. SPSS17.0 software was used for statistical processing and t-Test analysis was used. The results showed that Mean 卤SD was used as a significant difference between the two groups. Results:. 1. GLL LS2, LS3 and LS4 in hypertension group and uremia group were lower than those in normal control group. Except for LS2, the decrease in hypertension group was more obvious than that in uremia group, and the difference was statistically significant (P 0.05). 2.The peak time standard deviation of hypertension group and uremia group was longer than that of normal control group, the difference was statistically significant (P 0.05), but there was no significant difference between hypertension group and uremia group. 3.The peak of left ventricular longitudinal strain in patients with essential hypertension was lower than that in uremia patients with the same blood pressure level. Conclusion:. 1left ventricular wall motion in patients with uremia and essential hypertension was different from that in normal subjects, and myocardial deformability was more obvious in patients with essential hypertension. 2STI technique can accurately evaluate the longitudinal strain of left ventricular myocardium in uremic patients and essential hypertension patients. 3STI can indirectly reflect the different effects of uremia and essential hypertension on myocardium.
【学位授予单位】：吉林大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R692.5;R544.11

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